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Infection and Spread

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Should those who have had COVID-19 and recovered be issued an “immunity passport” or “risk-free certificate”?

Biology/Immunity Infection and Spread

A: The World Health Organization states, “At this point in the pandemic, there is not enough evidence about the effectiveness of antibody-mediated immunity to guarantee the accuracy of an “immunity passport” or “risk-free certificate.”” Main reasons why: Laboratory tests that detect antibodies to SARS-CoV-2 in people need further validation to determine their accuracy and reliability Read more…

Could over 20% of individuals living in New York City really already have been exposed to COVID-19?

Biology/Immunity Infection and Spread

A: Possibly, but there are a few things to consider about the sample of individuals included in the study (and all sero-surveys assessing past exposure to the infection via detection of antibodies targeted against SARS-CoV-2). In this study, ~3000 individuals (~1300 in NYC specifically) were recruited to be tested for presence of antibodies targeted against Read more…

I keep hearing reports that a lab accident caused the pandemic. Is this true?

Infection and Spread Uncertainty and Misinformation

A: Experts agree: “Virtually no chance.” NPR canvassed ten leading researchers specializing in coronaviruses and/or lab accidents, all of whom share the view that this virus was first transmitted to humans by animals in a real-world setting. As Robert Garry, a microbiologist at Tulane, goes on to explain: “The virus is really too good at Read more…

I’m young(ish) and healthy, do I really need to worry about catching COVID-19?

Clinical Symptoms Infection and Spread

A: While the most serious risk for complications and mortality is still at older ages and those with co-morbidities, the course of disease in younger and middle-aged adults is proving highly unpredictable. “There’s a big difference in how people handle this virus,” says Robert Murphy, a professor of medicine and the director of the Center Read more…

I know I’ve been infected with COVID-19. How long am I contagious for and when can I come out of isolation?

Infection and Spread Staying Safe

A. Scientists still don’t know how long people remain contagious for after infection. The CDC has issued guidelines for when people with known COVID infection can leave the house for essential trips: No fever for at least 72 hours without the use of medicines to reduce the fever, AND Other symptoms have improved, AND At Read more…

What things should I consider if I want to move my loved one out of a nursing home or assisted living facility during the current pandemic?

Families/Kids Infection and Spread Staying Safe

A: Several factors make COVID-19 very dangerous to nursing home and assisted living residents. The virus can go undetected in staff and residents with no symptoms, facilitating rapid spread to older adults with underlying health conditions and their vital care providers. Like hospitals, adequate protective equipment and the capacity to test residents and staff are Read more…

What is an “infectious dose?” What is the “viral load”? Does high viral load increase ability to pass the virus to others?

Biology/Immunity Infection and Spread

A: Full explainer in the link below from two microbiology Profs. “In general, the more virus you have in your airways, the more you will release when you exhale or cough, although there is a lot of person-to-person variation. Multiple studies have reported that patients have the highest viral load of the coronavirus at the Read more…

What do individuals who are infected with coronavirus and are asymptomatic, pre-symptomatic or mildly symptomatic have in common?

Infection and Spread

A: All three types of infected individuals may be able to transmit coronavirus to others without realizing they themselves have been infected. ASYMPTOMATIC individuals are those that carry the active virus in their body but never develop any symptoms. PRE-SYMPTOMATIC individuals are those that have been infected with the virus but haven’t started to show Read more…

The numbers of cases and deaths in some parts of the country are looking better than expected. Did we overreact with all the distancing measures and closures?

Data and Metrics Infection and Spread

A: So much no. No, no, nopeity nope. It’s very tempting to Monday morning quarterback the decisions that cities and states have made over the past few weeks, and the recommendations from the CDC. The physical distancing measures, the school closures and the near total shut-down of the economy feel extreme, particularly given some glimmers Read more…

Why is everyone suddenly talking about the positivity rate? Is this positive psychology or something else?

Data and Metrics Data Literacy Infection and Spread Testing and Contact Tracing

A: Definitely not positive psychology! The positivity rate is simply the fraction of people who test positive for COVID-19 out of all the people who get tested. It is important because it is a rough indicator of how much of the true extent of COVID-19 infection is being detected and diagnosed. In other words, a Read more…