What’s in childhood vaccines?

Families/Kids Infectious Diseases Vaccines

Ingredients in childhood vaccines are safe and are also common in the environment and other household items.

The end of summer is a busy time of year for parents. With health visits and school supplies on the brain, vaccines are probably the last thing on most parents’ minds. But have you ever wondered about what’s in many childhood vaccines?

Most vaccines need more than their active ingredients to be shelf-stable and perform at their best. Two common ingredients found in vaccines as well as commercial products and the environment are polysorbate 80 and aluminum. Not only are these ingredients found in many household items, but often in greater amounts than in routine shots.

NOTE: See Polysorbate 80 and Aluminum graphic below.

May be an image of text that says "I// Polysorbate 80 Emusifier: Prevents Clumping Aluminum Found in: Adjuvant: Allows AllowsSmallerVaccineDoses Smaller Vaccine Doses Found in: BODY LOTION BAKING POWDER Infant 1"

A third ingredient, Thimerosal, also known as ethyl mercury, is often found in multi-dose flu vaccine preparations. It is a harmless preservative used to prevent the growth of bacteria or fungus in a vaccine vial that is accessed more than once. Most manufacturers have moved towards single-use vials, which not only reduce vaccine wastage, but also eliminate the need for preservatives like thimerosal to prevent contamination.

NOTE: See Methyl vs. Ethyl graphic below.

May be an image of text

Thimerosal is no longer used in childhood vaccines, but is still used in many flu vaccines and adult/teen Tetanus (Td, NOT Tdap) shots. There is no thimerosal in COVID-19 vaccines or Fluarix (a pediatric flu formulation). Thimerosal has gotten a bad rap partly because of its similarity in name to methyl mercury, which is incredibly toxic. Ethyl and methyl groups differ by only 2 hydrogens and a carbon, but these little letters make a big difference. Ethyl mercury is non-toxic and is quickly broken down and excreted by the body while methyl mercury is bad news-it can accumulate in tissues and in certain doses can cause damage to the nervous system and kidneys.

NOTE: See Childhood Vaccines with Polysorbate 80 and Aluminum graphic below.

May be an image of text that says "2,4,6 +12-15 months Hib (H.flu bacteria) Pneumonia (Cν) +15-18m tage 4-6 Diphtheria-Tetanu Tetanus (DTap/Tdap) Childhood Vaccines with Polysorbate 80 and Aluminum 0,2, +6-18m 18m Hepatitis B (3 doses) 12-18m Hepatitis A (2 doses) age 9-14 HPV (2-3 doses)"

Stay nerdy. Stay well.

Those Nerdy Girls

Additional reading:

The Children’s Hospital of Philadelphia: Vaccine Ingredients

Vaccine Education Center at Children’s Hospital of Philadelphia: Aluminum & Vaccines: 3 Things to Know

Voices for Vaccines: Vaccine Ingredients

FDA: Thimerosal, vaccines, and safety

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