Is Bamlanivimab effective in the treatment of COVID-19?
Treatments
Sarah Whitley Coles, MD
A: Currently, the evidence is not yet clear, and we need lots more data. The FDA issued an Emergency Use Authorization (EUA) for bamlanivimab use in non-hospitalized patients with mild to moderate COVID-19 on November 9th. Bamlanivimab is a neutralizing monoclonal antibody that targets the spike protein on the SARS-CoV-2 virus. The goal of neutralizing Read more…
November 27, 2020
Well, here it is. I got COVID19. What can I do to take care of myself?
Treatments
Sarah Whitley Coles, MD
A: Taking care of yourself and focusing on getting better is priority #1! Get rest, stay hydrated, isolate physically but connect emotionally, and watch out for warning signs. COVID19 is widespread and more and more folks are getting sick. Now is a good time to remind ourselves of the basics of self-care when diagnosed with Read more…
November 23, 2020
Can SARS-CoV-2 infection be passed to babies in breastmilk?
Families/Kids Infection and Spread Treatments
Ashley Ritter, APRN, PhD
A: There is no evidence that SARS-CoV-2 infection can pass to babies via breastmilk with NEW findings to suggest breastmilk in mothers who have had Covid-19 contains specific SARS-CoV-2 antibodies. Insert tiny happy dance here. A recent study of breastmilk in 15 women who had recovered from Covid-19 found specific antibodies to the virus in Read more…
November 9, 2020
What are the chances that I’ll be hospitalized if I get COVID-19?
Data and Metrics Data Literacy Infection and Spread Treatments
Malia Jones, PhD MPH
A: The risk of ending up in the hospital for COVID-19 varies quite a bit by age. Based on data from the state of Wisconsin, the chances of being hospitalized (given that you’ve had a positive test for COVID-19) range from 1 in 100 for kids to 1 in 3 for people aged 80 and Read more…
October 24, 2020
Dear Pandemic COVID Q&A
Masks Staying Safe Treatments Videos
Malia Jones, PhD MPH
Dr. Lindsey Leininger and Dr. Malia Jones tackle questions about COVID from readers in this live Facebook event. ➡️ Intro and (grim) state of the pandemic: :01 – 1:56 ➡️ Lightning round: 2:30 – 5:40 ➡️ Treatment update: 5:45 – 12:05 ➡️ Outdoor masking: 12:10 – 16:20 ➡️ Malia saves Halloween!: 17:00 – 23:00
October 18, 2020
Could you speak to the issue of Elderberry Syrup and COVID?
Treatments
Q: We’re entering the season where I typically give it to my family as a flu prevention, but I’ve read that it can aggravate some COVID symptoms.” A: No scientific studies have been done using elderberry syrup to prevent or treat COVID-19. Similarly, there has been no information on whether elderberry syrup has negative impacts Read more…
October 16, 2020
I’ve been exposed. Is there a treatment that can keep me from getting sick?
Treatments
Lindsey Leininger, PhD MA
A: Not currently. But there’s hope in the clinical trial pipeline. For many viral diseases, treatment with a prescribed “post-exposure prophylaxis” (PEP) can block an exposure from developing into a full-blown infection. Tamiflu is perhaps the best-known example. TL;DR about PEP prospects for COVID-19: ✔️ Several older drugs repurposed for COVID-19 PEP have failed in Read more…
October 8, 2020
What are the “really good drugs and knowledge” that Trump tweeted about? Can I get these drugs if I get COVID-19?
Treatments
A: Not quite. The drugs that Donald Trump received after contracting COVID-19 are either still in clinical trials or available in limited quantities for people with serious infections. Trump received a level of treatment that is not available to the general public yet. While scientists have developed lots of new knowledge to better manage infections, Read more…
September 25, 2020
What’s the hoopla about monoclonal neutralizing antibody therapies?
Biology/Immunity Treatments
Malia Jones, PhD MPH
A: In short, neutralizing monoclonal antibodies are specialized proteins that can stop a particular virus from entering a cell and using it to make lots of copies of itself. Drug companies are developing a few different monoclonal antibodies intended to both prevent and treat COVID-19. When a virus gets inside your body and is identified Read more…
August 21, 2020
Can using a neti pot help prevent SARS-CoV-2 infection?
Staying Safe Treatments
Jennifer Beam Dowd, PhD
A: Possibly. There is no specific evidence for COVID-19 yet, but use of a neti pot *may* provide a benefit with limited risks. But don’t use it as a replacement for any other preventive measures. Neti pots are a type of “nasal irrigation” that are used to help clear sinuses and treat symptoms of allergies, Read more…
August 20, 2020
Is blood plasma a cure for COVID19?
Treatments
Sandra Albrecht, PhD MPH
A. The evidence suggests it’s still not clear. For today’s #TBT, we’re revisiting our previous post from May 12 which summarized the history, rationale, evidence to date around the use of blood plasma (also referred to as convalescent plasma) to treat COVID19. This was also a popular question from our weekly roundup, *and* it’s been Read more…
July 31, 2020
Hydroxychloroquine – yay or nay?
Treatments Uncertainty and Misinformation
Lindsey Leininger, PhD MA
A: The best evidence (still) suggests a resounding nay. ***** EDITED: 11:44 am to include FDA evidence review in the reference section ******* For our TGIF post we’re going to revisit the hydroxychloroquine (HCQ) debate, because let’s get real, friends…..it’s been quite the week on the HCQ information frontlines. We Nerdy Girls are here to Read more…
July 6, 2020
HYDROXYCHLOROQUINE FOR HOSPITALIZED COVID PATIENTS?
Treatments Uncertainty and Misinformation
Lindsey Leininger, PhD MA
THE DATA (STILL) SUGGEST “NO” New data out of the Detroit area find that hospitalized COVID patients receiving hydroxychloroquine (HCQ) were less likely to die than those not receiving the drug. Sensational headlines ensued. The scientific community sighed in disappointment and frustration. Why? (1) Administration of HCQ was NOT RANDOMIZED (2) The HCQ and non-HCQ Read more…
July 5, 2020
What have we learned about treatment of Covid-19 to date?
Treatments
Ashley Ritter, APRN, PhD
A: New discoveries happen every day! In addition to research taking place to develop a vaccine, many clinicians and researchers are learning more about how to treat Covid-19 infection. The new knowledge about treatment falls into three categories: 1) pathophysiology of Covid-19 infection, 2) decreasing disease severity, and 3) minimizing long-term complications. Understanding the physiologic Read more…
June 24, 2020
How do I make sense of all of the treatments being tested in clinical trials?! I can’t keep up – anti-virals, anti-inflammatories, antibodies….OH MY.
Treatments
Lindsey Leininger, PhD MA
A: What a confusing jumble! We Nerdy Girls like to keep the following phrase in mind: TREATMENT TIMING MATTERS. Different treatments target different points in the disease course, as helpfully demonstrated in these figures. Punchline: We’ll need an entire bag of treatment tricks to beat this devilishly nasty disease. A little more context: First we Read more…
June 18, 2020
Can you tell me the story of Hydroxychloroquine again?
Treatments Uncertainty and Misinformation
Aparna Kumar, PhD CRNP MPH
A: Absolutely. To answer this question, we turn to the analysis of others….because we also love elevating others’ excellent and succinct work for you. This quick video by The Incidental Economist hits on the major points of the retracted studies and where we are now. It also ends on a hopeful message: “Science isn’t perfect. Read more…
June 16, 2020
Study On Use of Steroids to Reduce COVID-19 Deaths
Treatments
Lindsey Leininger, PhD MA
BREAKING NEWS: A well-designed study by a respectable research group has yielded preliminary results indicating that a common, inexpensive steroid reduced deaths among very ill patients hospitalized with COVID-19. Nerdy Girl initial reactions: (1) THE STUDY IS WELL-DESIGNED Using the 3 Cs Framework: COMPARISON, CHANCE, and CONTEXT a) There is a randomly assigned COMPARISON group Read more…
A: Currently, the evidence is not yet clear, and we need lots more data. The FDA issued an Emergency Use Authorization (EUA) for bamlanivimab use in non-hospitalized patients with mild to moderate COVID-19 on November 9th. Bamlanivimab is a neutralizing monoclonal antibody that targets the spike protein on the SARS-CoV-2 virus. The goal of neutralizing Read more…
Well, here it is. I got COVID19. What can I do to take care of myself?
Treatments
Sarah Whitley Coles, MD
A: Taking care of yourself and focusing on getting better is priority #1! Get rest, stay hydrated, isolate physically but connect emotionally, and watch out for warning signs. COVID19 is widespread and more and more folks are getting sick. Now is a good time to remind ourselves of the basics of self-care when diagnosed with Read more…
November 23, 2020
Can SARS-CoV-2 infection be passed to babies in breastmilk?
Families/Kids Infection and Spread Treatments
Ashley Ritter, APRN, PhD
A: There is no evidence that SARS-CoV-2 infection can pass to babies via breastmilk with NEW findings to suggest breastmilk in mothers who have had Covid-19 contains specific SARS-CoV-2 antibodies. Insert tiny happy dance here. A recent study of breastmilk in 15 women who had recovered from Covid-19 found specific antibodies to the virus in Read more…
November 9, 2020
What are the chances that I’ll be hospitalized if I get COVID-19?
Data and Metrics Data Literacy Infection and Spread Treatments
Malia Jones, PhD MPH
A: The risk of ending up in the hospital for COVID-19 varies quite a bit by age. Based on data from the state of Wisconsin, the chances of being hospitalized (given that you’ve had a positive test for COVID-19) range from 1 in 100 for kids to 1 in 3 for people aged 80 and Read more…
October 24, 2020
Dear Pandemic COVID Q&A
Masks Staying Safe Treatments Videos
Malia Jones, PhD MPH
Dr. Lindsey Leininger and Dr. Malia Jones tackle questions about COVID from readers in this live Facebook event. ➡️ Intro and (grim) state of the pandemic: :01 – 1:56 ➡️ Lightning round: 2:30 – 5:40 ➡️ Treatment update: 5:45 – 12:05 ➡️ Outdoor masking: 12:10 – 16:20 ➡️ Malia saves Halloween!: 17:00 – 23:00
October 18, 2020
Could you speak to the issue of Elderberry Syrup and COVID?
Treatments
Q: We’re entering the season where I typically give it to my family as a flu prevention, but I’ve read that it can aggravate some COVID symptoms.” A: No scientific studies have been done using elderberry syrup to prevent or treat COVID-19. Similarly, there has been no information on whether elderberry syrup has negative impacts Read more…
October 16, 2020
I’ve been exposed. Is there a treatment that can keep me from getting sick?
Treatments
Lindsey Leininger, PhD MA
A: Not currently. But there’s hope in the clinical trial pipeline. For many viral diseases, treatment with a prescribed “post-exposure prophylaxis” (PEP) can block an exposure from developing into a full-blown infection. Tamiflu is perhaps the best-known example. TL;DR about PEP prospects for COVID-19: ✔️ Several older drugs repurposed for COVID-19 PEP have failed in Read more…
October 8, 2020
What are the “really good drugs and knowledge” that Trump tweeted about? Can I get these drugs if I get COVID-19?
Treatments
A: Not quite. The drugs that Donald Trump received after contracting COVID-19 are either still in clinical trials or available in limited quantities for people with serious infections. Trump received a level of treatment that is not available to the general public yet. While scientists have developed lots of new knowledge to better manage infections, Read more…
September 25, 2020
What’s the hoopla about monoclonal neutralizing antibody therapies?
Biology/Immunity Treatments
Malia Jones, PhD MPH
A: In short, neutralizing monoclonal antibodies are specialized proteins that can stop a particular virus from entering a cell and using it to make lots of copies of itself. Drug companies are developing a few different monoclonal antibodies intended to both prevent and treat COVID-19. When a virus gets inside your body and is identified Read more…
August 21, 2020
Can using a neti pot help prevent SARS-CoV-2 infection?
Staying Safe Treatments
Jennifer Beam Dowd, PhD
A: Possibly. There is no specific evidence for COVID-19 yet, but use of a neti pot *may* provide a benefit with limited risks. But don’t use it as a replacement for any other preventive measures. Neti pots are a type of “nasal irrigation” that are used to help clear sinuses and treat symptoms of allergies, Read more…
August 20, 2020
Is blood plasma a cure for COVID19?
Treatments
Sandra Albrecht, PhD MPH
A. The evidence suggests it’s still not clear. For today’s #TBT, we’re revisiting our previous post from May 12 which summarized the history, rationale, evidence to date around the use of blood plasma (also referred to as convalescent plasma) to treat COVID19. This was also a popular question from our weekly roundup, *and* it’s been Read more…
July 31, 2020
Hydroxychloroquine – yay or nay?
Treatments Uncertainty and Misinformation
Lindsey Leininger, PhD MA
A: The best evidence (still) suggests a resounding nay. ***** EDITED: 11:44 am to include FDA evidence review in the reference section ******* For our TGIF post we’re going to revisit the hydroxychloroquine (HCQ) debate, because let’s get real, friends…..it’s been quite the week on the HCQ information frontlines. We Nerdy Girls are here to Read more…
July 6, 2020
HYDROXYCHLOROQUINE FOR HOSPITALIZED COVID PATIENTS?
Treatments Uncertainty and Misinformation
Lindsey Leininger, PhD MA
THE DATA (STILL) SUGGEST “NO” New data out of the Detroit area find that hospitalized COVID patients receiving hydroxychloroquine (HCQ) were less likely to die than those not receiving the drug. Sensational headlines ensued. The scientific community sighed in disappointment and frustration. Why? (1) Administration of HCQ was NOT RANDOMIZED (2) The HCQ and non-HCQ Read more…
July 5, 2020
What have we learned about treatment of Covid-19 to date?
Treatments
Ashley Ritter, APRN, PhD
A: New discoveries happen every day! In addition to research taking place to develop a vaccine, many clinicians and researchers are learning more about how to treat Covid-19 infection. The new knowledge about treatment falls into three categories: 1) pathophysiology of Covid-19 infection, 2) decreasing disease severity, and 3) minimizing long-term complications. Understanding the physiologic Read more…
June 24, 2020
How do I make sense of all of the treatments being tested in clinical trials?! I can’t keep up – anti-virals, anti-inflammatories, antibodies….OH MY.
Treatments
Lindsey Leininger, PhD MA
A: What a confusing jumble! We Nerdy Girls like to keep the following phrase in mind: TREATMENT TIMING MATTERS. Different treatments target different points in the disease course, as helpfully demonstrated in these figures. Punchline: We’ll need an entire bag of treatment tricks to beat this devilishly nasty disease. A little more context: First we Read more…
June 18, 2020
Can you tell me the story of Hydroxychloroquine again?
Treatments Uncertainty and Misinformation
Aparna Kumar, PhD CRNP MPH
A: Absolutely. To answer this question, we turn to the analysis of others….because we also love elevating others’ excellent and succinct work for you. This quick video by The Incidental Economist hits on the major points of the retracted studies and where we are now. It also ends on a hopeful message: “Science isn’t perfect. Read more…
June 16, 2020
Study On Use of Steroids to Reduce COVID-19 Deaths
Treatments
Lindsey Leininger, PhD MA
BREAKING NEWS: A well-designed study by a respectable research group has yielded preliminary results indicating that a common, inexpensive steroid reduced deaths among very ill patients hospitalized with COVID-19. Nerdy Girl initial reactions: (1) THE STUDY IS WELL-DESIGNED Using the 3 Cs Framework: COMPARISON, CHANCE, and CONTEXT a) There is a randomly assigned COMPARISON group Read more…
A: Taking care of yourself and focusing on getting better is priority #1! Get rest, stay hydrated, isolate physically but connect emotionally, and watch out for warning signs. COVID19 is widespread and more and more folks are getting sick. Now is a good time to remind ourselves of the basics of self-care when diagnosed with Read more…
Can SARS-CoV-2 infection be passed to babies in breastmilk?
Families/Kids Infection and Spread Treatments
Ashley Ritter, APRN, PhD
A: There is no evidence that SARS-CoV-2 infection can pass to babies via breastmilk with NEW findings to suggest breastmilk in mothers who have had Covid-19 contains specific SARS-CoV-2 antibodies. Insert tiny happy dance here. A recent study of breastmilk in 15 women who had recovered from Covid-19 found specific antibodies to the virus in Read more…
November 9, 2020
What are the chances that I’ll be hospitalized if I get COVID-19?
Data and Metrics Data Literacy Infection and Spread Treatments
Malia Jones, PhD MPH
A: The risk of ending up in the hospital for COVID-19 varies quite a bit by age. Based on data from the state of Wisconsin, the chances of being hospitalized (given that you’ve had a positive test for COVID-19) range from 1 in 100 for kids to 1 in 3 for people aged 80 and Read more…
October 24, 2020
Dear Pandemic COVID Q&A
Masks Staying Safe Treatments Videos
Malia Jones, PhD MPH
Dr. Lindsey Leininger and Dr. Malia Jones tackle questions about COVID from readers in this live Facebook event. ➡️ Intro and (grim) state of the pandemic: :01 – 1:56 ➡️ Lightning round: 2:30 – 5:40 ➡️ Treatment update: 5:45 – 12:05 ➡️ Outdoor masking: 12:10 – 16:20 ➡️ Malia saves Halloween!: 17:00 – 23:00
October 18, 2020
Could you speak to the issue of Elderberry Syrup and COVID?
Treatments
Q: We’re entering the season where I typically give it to my family as a flu prevention, but I’ve read that it can aggravate some COVID symptoms.” A: No scientific studies have been done using elderberry syrup to prevent or treat COVID-19. Similarly, there has been no information on whether elderberry syrup has negative impacts Read more…
October 16, 2020
I’ve been exposed. Is there a treatment that can keep me from getting sick?
Treatments
Lindsey Leininger, PhD MA
A: Not currently. But there’s hope in the clinical trial pipeline. For many viral diseases, treatment with a prescribed “post-exposure prophylaxis” (PEP) can block an exposure from developing into a full-blown infection. Tamiflu is perhaps the best-known example. TL;DR about PEP prospects for COVID-19: ✔️ Several older drugs repurposed for COVID-19 PEP have failed in Read more…
October 8, 2020
What are the “really good drugs and knowledge” that Trump tweeted about? Can I get these drugs if I get COVID-19?
Treatments
A: Not quite. The drugs that Donald Trump received after contracting COVID-19 are either still in clinical trials or available in limited quantities for people with serious infections. Trump received a level of treatment that is not available to the general public yet. While scientists have developed lots of new knowledge to better manage infections, Read more…
September 25, 2020
What’s the hoopla about monoclonal neutralizing antibody therapies?
Biology/Immunity Treatments
Malia Jones, PhD MPH
A: In short, neutralizing monoclonal antibodies are specialized proteins that can stop a particular virus from entering a cell and using it to make lots of copies of itself. Drug companies are developing a few different monoclonal antibodies intended to both prevent and treat COVID-19. When a virus gets inside your body and is identified Read more…
August 21, 2020
Can using a neti pot help prevent SARS-CoV-2 infection?
Staying Safe Treatments
Jennifer Beam Dowd, PhD
A: Possibly. There is no specific evidence for COVID-19 yet, but use of a neti pot *may* provide a benefit with limited risks. But don’t use it as a replacement for any other preventive measures. Neti pots are a type of “nasal irrigation” that are used to help clear sinuses and treat symptoms of allergies, Read more…
August 20, 2020
Is blood plasma a cure for COVID19?
Treatments
Sandra Albrecht, PhD MPH
A. The evidence suggests it’s still not clear. For today’s #TBT, we’re revisiting our previous post from May 12 which summarized the history, rationale, evidence to date around the use of blood plasma (also referred to as convalescent plasma) to treat COVID19. This was also a popular question from our weekly roundup, *and* it’s been Read more…
July 31, 2020
Hydroxychloroquine – yay or nay?
Treatments Uncertainty and Misinformation
Lindsey Leininger, PhD MA
A: The best evidence (still) suggests a resounding nay. ***** EDITED: 11:44 am to include FDA evidence review in the reference section ******* For our TGIF post we’re going to revisit the hydroxychloroquine (HCQ) debate, because let’s get real, friends…..it’s been quite the week on the HCQ information frontlines. We Nerdy Girls are here to Read more…
July 6, 2020
HYDROXYCHLOROQUINE FOR HOSPITALIZED COVID PATIENTS?
Treatments Uncertainty and Misinformation
Lindsey Leininger, PhD MA
THE DATA (STILL) SUGGEST “NO” New data out of the Detroit area find that hospitalized COVID patients receiving hydroxychloroquine (HCQ) were less likely to die than those not receiving the drug. Sensational headlines ensued. The scientific community sighed in disappointment and frustration. Why? (1) Administration of HCQ was NOT RANDOMIZED (2) The HCQ and non-HCQ Read more…
July 5, 2020
What have we learned about treatment of Covid-19 to date?
Treatments
Ashley Ritter, APRN, PhD
A: New discoveries happen every day! In addition to research taking place to develop a vaccine, many clinicians and researchers are learning more about how to treat Covid-19 infection. The new knowledge about treatment falls into three categories: 1) pathophysiology of Covid-19 infection, 2) decreasing disease severity, and 3) minimizing long-term complications. Understanding the physiologic Read more…
June 24, 2020
How do I make sense of all of the treatments being tested in clinical trials?! I can’t keep up – anti-virals, anti-inflammatories, antibodies….OH MY.
Treatments
Lindsey Leininger, PhD MA
A: What a confusing jumble! We Nerdy Girls like to keep the following phrase in mind: TREATMENT TIMING MATTERS. Different treatments target different points in the disease course, as helpfully demonstrated in these figures. Punchline: We’ll need an entire bag of treatment tricks to beat this devilishly nasty disease. A little more context: First we Read more…
June 18, 2020
Can you tell me the story of Hydroxychloroquine again?
Treatments Uncertainty and Misinformation
Aparna Kumar, PhD CRNP MPH
A: Absolutely. To answer this question, we turn to the analysis of others….because we also love elevating others’ excellent and succinct work for you. This quick video by The Incidental Economist hits on the major points of the retracted studies and where we are now. It also ends on a hopeful message: “Science isn’t perfect. Read more…
June 16, 2020
Study On Use of Steroids to Reduce COVID-19 Deaths
Treatments
Lindsey Leininger, PhD MA
BREAKING NEWS: A well-designed study by a respectable research group has yielded preliminary results indicating that a common, inexpensive steroid reduced deaths among very ill patients hospitalized with COVID-19. Nerdy Girl initial reactions: (1) THE STUDY IS WELL-DESIGNED Using the 3 Cs Framework: COMPARISON, CHANCE, and CONTEXT a) There is a randomly assigned COMPARISON group Read more…
A: There is no evidence that SARS-CoV-2 infection can pass to babies via breastmilk with NEW findings to suggest breastmilk in mothers who have had Covid-19 contains specific SARS-CoV-2 antibodies. Insert tiny happy dance here. A recent study of breastmilk in 15 women who had recovered from Covid-19 found specific antibodies to the virus in Read more…
What are the chances that I’ll be hospitalized if I get COVID-19?
Data and Metrics Data Literacy Infection and Spread Treatments
Malia Jones, PhD MPH
A: The risk of ending up in the hospital for COVID-19 varies quite a bit by age. Based on data from the state of Wisconsin, the chances of being hospitalized (given that you’ve had a positive test for COVID-19) range from 1 in 100 for kids to 1 in 3 for people aged 80 and Read more…
October 24, 2020
Dear Pandemic COVID Q&A
Masks Staying Safe Treatments Videos
Malia Jones, PhD MPH
Dr. Lindsey Leininger and Dr. Malia Jones tackle questions about COVID from readers in this live Facebook event. ➡️ Intro and (grim) state of the pandemic: :01 – 1:56 ➡️ Lightning round: 2:30 – 5:40 ➡️ Treatment update: 5:45 – 12:05 ➡️ Outdoor masking: 12:10 – 16:20 ➡️ Malia saves Halloween!: 17:00 – 23:00
October 18, 2020
Could you speak to the issue of Elderberry Syrup and COVID?
Treatments
Q: We’re entering the season where I typically give it to my family as a flu prevention, but I’ve read that it can aggravate some COVID symptoms.” A: No scientific studies have been done using elderberry syrup to prevent or treat COVID-19. Similarly, there has been no information on whether elderberry syrup has negative impacts Read more…
October 16, 2020
I’ve been exposed. Is there a treatment that can keep me from getting sick?
Treatments
Lindsey Leininger, PhD MA
A: Not currently. But there’s hope in the clinical trial pipeline. For many viral diseases, treatment with a prescribed “post-exposure prophylaxis” (PEP) can block an exposure from developing into a full-blown infection. Tamiflu is perhaps the best-known example. TL;DR about PEP prospects for COVID-19: ✔️ Several older drugs repurposed for COVID-19 PEP have failed in Read more…
October 8, 2020
What are the “really good drugs and knowledge” that Trump tweeted about? Can I get these drugs if I get COVID-19?
Treatments
A: Not quite. The drugs that Donald Trump received after contracting COVID-19 are either still in clinical trials or available in limited quantities for people with serious infections. Trump received a level of treatment that is not available to the general public yet. While scientists have developed lots of new knowledge to better manage infections, Read more…
September 25, 2020
What’s the hoopla about monoclonal neutralizing antibody therapies?
Biology/Immunity Treatments
Malia Jones, PhD MPH
A: In short, neutralizing monoclonal antibodies are specialized proteins that can stop a particular virus from entering a cell and using it to make lots of copies of itself. Drug companies are developing a few different monoclonal antibodies intended to both prevent and treat COVID-19. When a virus gets inside your body and is identified Read more…
August 21, 2020
Can using a neti pot help prevent SARS-CoV-2 infection?
Staying Safe Treatments
Jennifer Beam Dowd, PhD
A: Possibly. There is no specific evidence for COVID-19 yet, but use of a neti pot *may* provide a benefit with limited risks. But don’t use it as a replacement for any other preventive measures. Neti pots are a type of “nasal irrigation” that are used to help clear sinuses and treat symptoms of allergies, Read more…
August 20, 2020
Is blood plasma a cure for COVID19?
Treatments
Sandra Albrecht, PhD MPH
A. The evidence suggests it’s still not clear. For today’s #TBT, we’re revisiting our previous post from May 12 which summarized the history, rationale, evidence to date around the use of blood plasma (also referred to as convalescent plasma) to treat COVID19. This was also a popular question from our weekly roundup, *and* it’s been Read more…
July 31, 2020
Hydroxychloroquine – yay or nay?
Treatments Uncertainty and Misinformation
Lindsey Leininger, PhD MA
A: The best evidence (still) suggests a resounding nay. ***** EDITED: 11:44 am to include FDA evidence review in the reference section ******* For our TGIF post we’re going to revisit the hydroxychloroquine (HCQ) debate, because let’s get real, friends…..it’s been quite the week on the HCQ information frontlines. We Nerdy Girls are here to Read more…
July 6, 2020
HYDROXYCHLOROQUINE FOR HOSPITALIZED COVID PATIENTS?
Treatments Uncertainty and Misinformation
Lindsey Leininger, PhD MA
THE DATA (STILL) SUGGEST “NO” New data out of the Detroit area find that hospitalized COVID patients receiving hydroxychloroquine (HCQ) were less likely to die than those not receiving the drug. Sensational headlines ensued. The scientific community sighed in disappointment and frustration. Why? (1) Administration of HCQ was NOT RANDOMIZED (2) The HCQ and non-HCQ Read more…
July 5, 2020
What have we learned about treatment of Covid-19 to date?
Treatments
Ashley Ritter, APRN, PhD
A: New discoveries happen every day! In addition to research taking place to develop a vaccine, many clinicians and researchers are learning more about how to treat Covid-19 infection. The new knowledge about treatment falls into three categories: 1) pathophysiology of Covid-19 infection, 2) decreasing disease severity, and 3) minimizing long-term complications. Understanding the physiologic Read more…
June 24, 2020
How do I make sense of all of the treatments being tested in clinical trials?! I can’t keep up – anti-virals, anti-inflammatories, antibodies….OH MY.
Treatments
Lindsey Leininger, PhD MA
A: What a confusing jumble! We Nerdy Girls like to keep the following phrase in mind: TREATMENT TIMING MATTERS. Different treatments target different points in the disease course, as helpfully demonstrated in these figures. Punchline: We’ll need an entire bag of treatment tricks to beat this devilishly nasty disease. A little more context: First we Read more…
June 18, 2020
Can you tell me the story of Hydroxychloroquine again?
Treatments Uncertainty and Misinformation
Aparna Kumar, PhD CRNP MPH
A: Absolutely. To answer this question, we turn to the analysis of others….because we also love elevating others’ excellent and succinct work for you. This quick video by The Incidental Economist hits on the major points of the retracted studies and where we are now. It also ends on a hopeful message: “Science isn’t perfect. Read more…
June 16, 2020
Study On Use of Steroids to Reduce COVID-19 Deaths
Treatments
Lindsey Leininger, PhD MA
BREAKING NEWS: A well-designed study by a respectable research group has yielded preliminary results indicating that a common, inexpensive steroid reduced deaths among very ill patients hospitalized with COVID-19. Nerdy Girl initial reactions: (1) THE STUDY IS WELL-DESIGNED Using the 3 Cs Framework: COMPARISON, CHANCE, and CONTEXT a) There is a randomly assigned COMPARISON group Read more…
A: The risk of ending up in the hospital for COVID-19 varies quite a bit by age. Based on data from the state of Wisconsin, the chances of being hospitalized (given that you’ve had a positive test for COVID-19) range from 1 in 100 for kids to 1 in 3 for people aged 80 and Read more…
Dear Pandemic COVID Q&A
Masks Staying Safe Treatments Videos
Malia Jones, PhD MPH
Dr. Lindsey Leininger and Dr. Malia Jones tackle questions about COVID from readers in this live Facebook event. ➡️ Intro and (grim) state of the pandemic: :01 – 1:56 ➡️ Lightning round: 2:30 – 5:40 ➡️ Treatment update: 5:45 – 12:05 ➡️ Outdoor masking: 12:10 – 16:20 ➡️ Malia saves Halloween!: 17:00 – 23:00
October 18, 2020
Could you speak to the issue of Elderberry Syrup and COVID?
Treatments
Q: We’re entering the season where I typically give it to my family as a flu prevention, but I’ve read that it can aggravate some COVID symptoms.” A: No scientific studies have been done using elderberry syrup to prevent or treat COVID-19. Similarly, there has been no information on whether elderberry syrup has negative impacts Read more…
October 16, 2020
I’ve been exposed. Is there a treatment that can keep me from getting sick?
Treatments
Lindsey Leininger, PhD MA
A: Not currently. But there’s hope in the clinical trial pipeline. For many viral diseases, treatment with a prescribed “post-exposure prophylaxis” (PEP) can block an exposure from developing into a full-blown infection. Tamiflu is perhaps the best-known example. TL;DR about PEP prospects for COVID-19: ✔️ Several older drugs repurposed for COVID-19 PEP have failed in Read more…
October 8, 2020
What are the “really good drugs and knowledge” that Trump tweeted about? Can I get these drugs if I get COVID-19?
Treatments
A: Not quite. The drugs that Donald Trump received after contracting COVID-19 are either still in clinical trials or available in limited quantities for people with serious infections. Trump received a level of treatment that is not available to the general public yet. While scientists have developed lots of new knowledge to better manage infections, Read more…
September 25, 2020
What’s the hoopla about monoclonal neutralizing antibody therapies?
Biology/Immunity Treatments
Malia Jones, PhD MPH
A: In short, neutralizing monoclonal antibodies are specialized proteins that can stop a particular virus from entering a cell and using it to make lots of copies of itself. Drug companies are developing a few different monoclonal antibodies intended to both prevent and treat COVID-19. When a virus gets inside your body and is identified Read more…
August 21, 2020
Can using a neti pot help prevent SARS-CoV-2 infection?
Staying Safe Treatments
Jennifer Beam Dowd, PhD
A: Possibly. There is no specific evidence for COVID-19 yet, but use of a neti pot *may* provide a benefit with limited risks. But don’t use it as a replacement for any other preventive measures. Neti pots are a type of “nasal irrigation” that are used to help clear sinuses and treat symptoms of allergies, Read more…
August 20, 2020
Is blood plasma a cure for COVID19?
Treatments
Sandra Albrecht, PhD MPH
A. The evidence suggests it’s still not clear. For today’s #TBT, we’re revisiting our previous post from May 12 which summarized the history, rationale, evidence to date around the use of blood plasma (also referred to as convalescent plasma) to treat COVID19. This was also a popular question from our weekly roundup, *and* it’s been Read more…
July 31, 2020
Hydroxychloroquine – yay or nay?
Treatments Uncertainty and Misinformation
Lindsey Leininger, PhD MA
A: The best evidence (still) suggests a resounding nay. ***** EDITED: 11:44 am to include FDA evidence review in the reference section ******* For our TGIF post we’re going to revisit the hydroxychloroquine (HCQ) debate, because let’s get real, friends…..it’s been quite the week on the HCQ information frontlines. We Nerdy Girls are here to Read more…
July 6, 2020
HYDROXYCHLOROQUINE FOR HOSPITALIZED COVID PATIENTS?
Treatments Uncertainty and Misinformation
Lindsey Leininger, PhD MA
THE DATA (STILL) SUGGEST “NO” New data out of the Detroit area find that hospitalized COVID patients receiving hydroxychloroquine (HCQ) were less likely to die than those not receiving the drug. Sensational headlines ensued. The scientific community sighed in disappointment and frustration. Why? (1) Administration of HCQ was NOT RANDOMIZED (2) The HCQ and non-HCQ Read more…
July 5, 2020
What have we learned about treatment of Covid-19 to date?
Treatments
Ashley Ritter, APRN, PhD
A: New discoveries happen every day! In addition to research taking place to develop a vaccine, many clinicians and researchers are learning more about how to treat Covid-19 infection. The new knowledge about treatment falls into three categories: 1) pathophysiology of Covid-19 infection, 2) decreasing disease severity, and 3) minimizing long-term complications. Understanding the physiologic Read more…
June 24, 2020
How do I make sense of all of the treatments being tested in clinical trials?! I can’t keep up – anti-virals, anti-inflammatories, antibodies….OH MY.
Treatments
Lindsey Leininger, PhD MA
A: What a confusing jumble! We Nerdy Girls like to keep the following phrase in mind: TREATMENT TIMING MATTERS. Different treatments target different points in the disease course, as helpfully demonstrated in these figures. Punchline: We’ll need an entire bag of treatment tricks to beat this devilishly nasty disease. A little more context: First we Read more…
June 18, 2020
Can you tell me the story of Hydroxychloroquine again?
Treatments Uncertainty and Misinformation
Aparna Kumar, PhD CRNP MPH
A: Absolutely. To answer this question, we turn to the analysis of others….because we also love elevating others’ excellent and succinct work for you. This quick video by The Incidental Economist hits on the major points of the retracted studies and where we are now. It also ends on a hopeful message: “Science isn’t perfect. Read more…
June 16, 2020
Study On Use of Steroids to Reduce COVID-19 Deaths
Treatments
Lindsey Leininger, PhD MA
BREAKING NEWS: A well-designed study by a respectable research group has yielded preliminary results indicating that a common, inexpensive steroid reduced deaths among very ill patients hospitalized with COVID-19. Nerdy Girl initial reactions: (1) THE STUDY IS WELL-DESIGNED Using the 3 Cs Framework: COMPARISON, CHANCE, and CONTEXT a) There is a randomly assigned COMPARISON group Read more…
Dr. Lindsey Leininger and Dr. Malia Jones tackle questions about COVID from readers in this live Facebook event. ➡️ Intro and (grim) state of the pandemic: :01 – 1:56 ➡️ Lightning round: 2:30 – 5:40 ➡️ Treatment update: 5:45 – 12:05 ➡️ Outdoor masking: 12:10 – 16:20 ➡️ Malia saves Halloween!: 17:00 – 23:00
Could you speak to the issue of Elderberry Syrup and COVID?
TreatmentsQ: We’re entering the season where I typically give it to my family as a flu prevention, but I’ve read that it can aggravate some COVID symptoms.” A: No scientific studies have been done using elderberry syrup to prevent or treat COVID-19. Similarly, there has been no information on whether elderberry syrup has negative impacts Read more…
I’ve been exposed. Is there a treatment that can keep me from getting sick?
Treatments
Lindsey Leininger, PhD MA
A: Not currently. But there’s hope in the clinical trial pipeline. For many viral diseases, treatment with a prescribed “post-exposure prophylaxis” (PEP) can block an exposure from developing into a full-blown infection. Tamiflu is perhaps the best-known example. TL;DR about PEP prospects for COVID-19: ✔️ Several older drugs repurposed for COVID-19 PEP have failed in Read more…
October 8, 2020
What are the “really good drugs and knowledge” that Trump tweeted about? Can I get these drugs if I get COVID-19?
Treatments
A: Not quite. The drugs that Donald Trump received after contracting COVID-19 are either still in clinical trials or available in limited quantities for people with serious infections. Trump received a level of treatment that is not available to the general public yet. While scientists have developed lots of new knowledge to better manage infections, Read more…
September 25, 2020
What’s the hoopla about monoclonal neutralizing antibody therapies?
Biology/Immunity Treatments
Malia Jones, PhD MPH
A: In short, neutralizing monoclonal antibodies are specialized proteins that can stop a particular virus from entering a cell and using it to make lots of copies of itself. Drug companies are developing a few different monoclonal antibodies intended to both prevent and treat COVID-19. When a virus gets inside your body and is identified Read more…
August 21, 2020
Can using a neti pot help prevent SARS-CoV-2 infection?
Staying Safe Treatments
Jennifer Beam Dowd, PhD
A: Possibly. There is no specific evidence for COVID-19 yet, but use of a neti pot *may* provide a benefit with limited risks. But don’t use it as a replacement for any other preventive measures. Neti pots are a type of “nasal irrigation” that are used to help clear sinuses and treat symptoms of allergies, Read more…
August 20, 2020
Is blood plasma a cure for COVID19?
Treatments
Sandra Albrecht, PhD MPH
A. The evidence suggests it’s still not clear. For today’s #TBT, we’re revisiting our previous post from May 12 which summarized the history, rationale, evidence to date around the use of blood plasma (also referred to as convalescent plasma) to treat COVID19. This was also a popular question from our weekly roundup, *and* it’s been Read more…
July 31, 2020
Hydroxychloroquine – yay or nay?
Treatments Uncertainty and Misinformation
Lindsey Leininger, PhD MA
A: The best evidence (still) suggests a resounding nay. ***** EDITED: 11:44 am to include FDA evidence review in the reference section ******* For our TGIF post we’re going to revisit the hydroxychloroquine (HCQ) debate, because let’s get real, friends…..it’s been quite the week on the HCQ information frontlines. We Nerdy Girls are here to Read more…
July 6, 2020
HYDROXYCHLOROQUINE FOR HOSPITALIZED COVID PATIENTS?
Treatments Uncertainty and Misinformation
Lindsey Leininger, PhD MA
THE DATA (STILL) SUGGEST “NO” New data out of the Detroit area find that hospitalized COVID patients receiving hydroxychloroquine (HCQ) were less likely to die than those not receiving the drug. Sensational headlines ensued. The scientific community sighed in disappointment and frustration. Why? (1) Administration of HCQ was NOT RANDOMIZED (2) The HCQ and non-HCQ Read more…
July 5, 2020
What have we learned about treatment of Covid-19 to date?
Treatments
Ashley Ritter, APRN, PhD
A: New discoveries happen every day! In addition to research taking place to develop a vaccine, many clinicians and researchers are learning more about how to treat Covid-19 infection. The new knowledge about treatment falls into three categories: 1) pathophysiology of Covid-19 infection, 2) decreasing disease severity, and 3) minimizing long-term complications. Understanding the physiologic Read more…
June 24, 2020
How do I make sense of all of the treatments being tested in clinical trials?! I can’t keep up – anti-virals, anti-inflammatories, antibodies….OH MY.
Treatments
Lindsey Leininger, PhD MA
A: What a confusing jumble! We Nerdy Girls like to keep the following phrase in mind: TREATMENT TIMING MATTERS. Different treatments target different points in the disease course, as helpfully demonstrated in these figures. Punchline: We’ll need an entire bag of treatment tricks to beat this devilishly nasty disease. A little more context: First we Read more…
June 18, 2020
Can you tell me the story of Hydroxychloroquine again?
Treatments Uncertainty and Misinformation
Aparna Kumar, PhD CRNP MPH
A: Absolutely. To answer this question, we turn to the analysis of others….because we also love elevating others’ excellent and succinct work for you. This quick video by The Incidental Economist hits on the major points of the retracted studies and where we are now. It also ends on a hopeful message: “Science isn’t perfect. Read more…
June 16, 2020
Study On Use of Steroids to Reduce COVID-19 Deaths
Treatments
Lindsey Leininger, PhD MA
BREAKING NEWS: A well-designed study by a respectable research group has yielded preliminary results indicating that a common, inexpensive steroid reduced deaths among very ill patients hospitalized with COVID-19. Nerdy Girl initial reactions: (1) THE STUDY IS WELL-DESIGNED Using the 3 Cs Framework: COMPARISON, CHANCE, and CONTEXT a) There is a randomly assigned COMPARISON group Read more…
A: Not currently. But there’s hope in the clinical trial pipeline. For many viral diseases, treatment with a prescribed “post-exposure prophylaxis” (PEP) can block an exposure from developing into a full-blown infection. Tamiflu is perhaps the best-known example. TL;DR about PEP prospects for COVID-19: ✔️ Several older drugs repurposed for COVID-19 PEP have failed in Read more…
What are the “really good drugs and knowledge” that Trump tweeted about? Can I get these drugs if I get COVID-19?
TreatmentsA: Not quite. The drugs that Donald Trump received after contracting COVID-19 are either still in clinical trials or available in limited quantities for people with serious infections. Trump received a level of treatment that is not available to the general public yet. While scientists have developed lots of new knowledge to better manage infections, Read more…
What’s the hoopla about monoclonal neutralizing antibody therapies?
Biology/Immunity Treatments
Malia Jones, PhD MPH
A: In short, neutralizing monoclonal antibodies are specialized proteins that can stop a particular virus from entering a cell and using it to make lots of copies of itself. Drug companies are developing a few different monoclonal antibodies intended to both prevent and treat COVID-19. When a virus gets inside your body and is identified Read more…
August 21, 2020
Can using a neti pot help prevent SARS-CoV-2 infection?
Staying Safe Treatments
Jennifer Beam Dowd, PhD
A: Possibly. There is no specific evidence for COVID-19 yet, but use of a neti pot *may* provide a benefit with limited risks. But don’t use it as a replacement for any other preventive measures. Neti pots are a type of “nasal irrigation” that are used to help clear sinuses and treat symptoms of allergies, Read more…
August 20, 2020
Is blood plasma a cure for COVID19?
Treatments
Sandra Albrecht, PhD MPH
A. The evidence suggests it’s still not clear. For today’s #TBT, we’re revisiting our previous post from May 12 which summarized the history, rationale, evidence to date around the use of blood plasma (also referred to as convalescent plasma) to treat COVID19. This was also a popular question from our weekly roundup, *and* it’s been Read more…
July 31, 2020
Hydroxychloroquine – yay or nay?
Treatments Uncertainty and Misinformation
Lindsey Leininger, PhD MA
A: The best evidence (still) suggests a resounding nay. ***** EDITED: 11:44 am to include FDA evidence review in the reference section ******* For our TGIF post we’re going to revisit the hydroxychloroquine (HCQ) debate, because let’s get real, friends…..it’s been quite the week on the HCQ information frontlines. We Nerdy Girls are here to Read more…
July 6, 2020
HYDROXYCHLOROQUINE FOR HOSPITALIZED COVID PATIENTS?
Treatments Uncertainty and Misinformation
Lindsey Leininger, PhD MA
THE DATA (STILL) SUGGEST “NO” New data out of the Detroit area find that hospitalized COVID patients receiving hydroxychloroquine (HCQ) were less likely to die than those not receiving the drug. Sensational headlines ensued. The scientific community sighed in disappointment and frustration. Why? (1) Administration of HCQ was NOT RANDOMIZED (2) The HCQ and non-HCQ Read more…
July 5, 2020
What have we learned about treatment of Covid-19 to date?
Treatments
Ashley Ritter, APRN, PhD
A: New discoveries happen every day! In addition to research taking place to develop a vaccine, many clinicians and researchers are learning more about how to treat Covid-19 infection. The new knowledge about treatment falls into three categories: 1) pathophysiology of Covid-19 infection, 2) decreasing disease severity, and 3) minimizing long-term complications. Understanding the physiologic Read more…
June 24, 2020
How do I make sense of all of the treatments being tested in clinical trials?! I can’t keep up – anti-virals, anti-inflammatories, antibodies….OH MY.
Treatments
Lindsey Leininger, PhD MA
A: What a confusing jumble! We Nerdy Girls like to keep the following phrase in mind: TREATMENT TIMING MATTERS. Different treatments target different points in the disease course, as helpfully demonstrated in these figures. Punchline: We’ll need an entire bag of treatment tricks to beat this devilishly nasty disease. A little more context: First we Read more…
June 18, 2020
Can you tell me the story of Hydroxychloroquine again?
Treatments Uncertainty and Misinformation
Aparna Kumar, PhD CRNP MPH
A: Absolutely. To answer this question, we turn to the analysis of others….because we also love elevating others’ excellent and succinct work for you. This quick video by The Incidental Economist hits on the major points of the retracted studies and where we are now. It also ends on a hopeful message: “Science isn’t perfect. Read more…
June 16, 2020
Study On Use of Steroids to Reduce COVID-19 Deaths
Treatments
Lindsey Leininger, PhD MA
BREAKING NEWS: A well-designed study by a respectable research group has yielded preliminary results indicating that a common, inexpensive steroid reduced deaths among very ill patients hospitalized with COVID-19. Nerdy Girl initial reactions: (1) THE STUDY IS WELL-DESIGNED Using the 3 Cs Framework: COMPARISON, CHANCE, and CONTEXT a) There is a randomly assigned COMPARISON group Read more…
A: In short, neutralizing monoclonal antibodies are specialized proteins that can stop a particular virus from entering a cell and using it to make lots of copies of itself. Drug companies are developing a few different monoclonal antibodies intended to both prevent and treat COVID-19. When a virus gets inside your body and is identified Read more…
Can using a neti pot help prevent SARS-CoV-2 infection?
Staying Safe Treatments
Jennifer Beam Dowd, PhD
A: Possibly. There is no specific evidence for COVID-19 yet, but use of a neti pot *may* provide a benefit with limited risks. But don’t use it as a replacement for any other preventive measures. Neti pots are a type of “nasal irrigation” that are used to help clear sinuses and treat symptoms of allergies, Read more…
August 20, 2020
Is blood plasma a cure for COVID19?
Treatments
Sandra Albrecht, PhD MPH
A. The evidence suggests it’s still not clear. For today’s #TBT, we’re revisiting our previous post from May 12 which summarized the history, rationale, evidence to date around the use of blood plasma (also referred to as convalescent plasma) to treat COVID19. This was also a popular question from our weekly roundup, *and* it’s been Read more…
July 31, 2020
Hydroxychloroquine – yay or nay?
Treatments Uncertainty and Misinformation
Lindsey Leininger, PhD MA
A: The best evidence (still) suggests a resounding nay. ***** EDITED: 11:44 am to include FDA evidence review in the reference section ******* For our TGIF post we’re going to revisit the hydroxychloroquine (HCQ) debate, because let’s get real, friends…..it’s been quite the week on the HCQ information frontlines. We Nerdy Girls are here to Read more…
July 6, 2020
HYDROXYCHLOROQUINE FOR HOSPITALIZED COVID PATIENTS?
Treatments Uncertainty and Misinformation
Lindsey Leininger, PhD MA
THE DATA (STILL) SUGGEST “NO” New data out of the Detroit area find that hospitalized COVID patients receiving hydroxychloroquine (HCQ) were less likely to die than those not receiving the drug. Sensational headlines ensued. The scientific community sighed in disappointment and frustration. Why? (1) Administration of HCQ was NOT RANDOMIZED (2) The HCQ and non-HCQ Read more…
July 5, 2020
What have we learned about treatment of Covid-19 to date?
Treatments
Ashley Ritter, APRN, PhD
A: New discoveries happen every day! In addition to research taking place to develop a vaccine, many clinicians and researchers are learning more about how to treat Covid-19 infection. The new knowledge about treatment falls into three categories: 1) pathophysiology of Covid-19 infection, 2) decreasing disease severity, and 3) minimizing long-term complications. Understanding the physiologic Read more…
June 24, 2020
How do I make sense of all of the treatments being tested in clinical trials?! I can’t keep up – anti-virals, anti-inflammatories, antibodies….OH MY.
Treatments
Lindsey Leininger, PhD MA
A: What a confusing jumble! We Nerdy Girls like to keep the following phrase in mind: TREATMENT TIMING MATTERS. Different treatments target different points in the disease course, as helpfully demonstrated in these figures. Punchline: We’ll need an entire bag of treatment tricks to beat this devilishly nasty disease. A little more context: First we Read more…
June 18, 2020
Can you tell me the story of Hydroxychloroquine again?
Treatments Uncertainty and Misinformation
Aparna Kumar, PhD CRNP MPH
A: Absolutely. To answer this question, we turn to the analysis of others….because we also love elevating others’ excellent and succinct work for you. This quick video by The Incidental Economist hits on the major points of the retracted studies and where we are now. It also ends on a hopeful message: “Science isn’t perfect. Read more…
June 16, 2020
Study On Use of Steroids to Reduce COVID-19 Deaths
Treatments
Lindsey Leininger, PhD MA
BREAKING NEWS: A well-designed study by a respectable research group has yielded preliminary results indicating that a common, inexpensive steroid reduced deaths among very ill patients hospitalized with COVID-19. Nerdy Girl initial reactions: (1) THE STUDY IS WELL-DESIGNED Using the 3 Cs Framework: COMPARISON, CHANCE, and CONTEXT a) There is a randomly assigned COMPARISON group Read more…
A: Possibly. There is no specific evidence for COVID-19 yet, but use of a neti pot *may* provide a benefit with limited risks. But don’t use it as a replacement for any other preventive measures. Neti pots are a type of “nasal irrigation” that are used to help clear sinuses and treat symptoms of allergies, Read more…
Is blood plasma a cure for COVID19?
Treatments
Sandra Albrecht, PhD MPH
A. The evidence suggests it’s still not clear. For today’s #TBT, we’re revisiting our previous post from May 12 which summarized the history, rationale, evidence to date around the use of blood plasma (also referred to as convalescent plasma) to treat COVID19. This was also a popular question from our weekly roundup, *and* it’s been Read more…
July 31, 2020
Hydroxychloroquine – yay or nay?
Treatments Uncertainty and Misinformation
Lindsey Leininger, PhD MA
A: The best evidence (still) suggests a resounding nay. ***** EDITED: 11:44 am to include FDA evidence review in the reference section ******* For our TGIF post we’re going to revisit the hydroxychloroquine (HCQ) debate, because let’s get real, friends…..it’s been quite the week on the HCQ information frontlines. We Nerdy Girls are here to Read more…
July 6, 2020
HYDROXYCHLOROQUINE FOR HOSPITALIZED COVID PATIENTS?
Treatments Uncertainty and Misinformation
Lindsey Leininger, PhD MA
THE DATA (STILL) SUGGEST “NO” New data out of the Detroit area find that hospitalized COVID patients receiving hydroxychloroquine (HCQ) were less likely to die than those not receiving the drug. Sensational headlines ensued. The scientific community sighed in disappointment and frustration. Why? (1) Administration of HCQ was NOT RANDOMIZED (2) The HCQ and non-HCQ Read more…
July 5, 2020
What have we learned about treatment of Covid-19 to date?
Treatments
Ashley Ritter, APRN, PhD
A: New discoveries happen every day! In addition to research taking place to develop a vaccine, many clinicians and researchers are learning more about how to treat Covid-19 infection. The new knowledge about treatment falls into three categories: 1) pathophysiology of Covid-19 infection, 2) decreasing disease severity, and 3) minimizing long-term complications. Understanding the physiologic Read more…
June 24, 2020
How do I make sense of all of the treatments being tested in clinical trials?! I can’t keep up – anti-virals, anti-inflammatories, antibodies….OH MY.
Treatments
Lindsey Leininger, PhD MA
A: What a confusing jumble! We Nerdy Girls like to keep the following phrase in mind: TREATMENT TIMING MATTERS. Different treatments target different points in the disease course, as helpfully demonstrated in these figures. Punchline: We’ll need an entire bag of treatment tricks to beat this devilishly nasty disease. A little more context: First we Read more…
June 18, 2020
Can you tell me the story of Hydroxychloroquine again?
Treatments Uncertainty and Misinformation
Aparna Kumar, PhD CRNP MPH
A: Absolutely. To answer this question, we turn to the analysis of others….because we also love elevating others’ excellent and succinct work for you. This quick video by The Incidental Economist hits on the major points of the retracted studies and where we are now. It also ends on a hopeful message: “Science isn’t perfect. Read more…
June 16, 2020
Study On Use of Steroids to Reduce COVID-19 Deaths
Treatments
Lindsey Leininger, PhD MA
BREAKING NEWS: A well-designed study by a respectable research group has yielded preliminary results indicating that a common, inexpensive steroid reduced deaths among very ill patients hospitalized with COVID-19. Nerdy Girl initial reactions: (1) THE STUDY IS WELL-DESIGNED Using the 3 Cs Framework: COMPARISON, CHANCE, and CONTEXT a) There is a randomly assigned COMPARISON group Read more…
A. The evidence suggests it’s still not clear. For today’s #TBT, we’re revisiting our previous post from May 12 which summarized the history, rationale, evidence to date around the use of blood plasma (also referred to as convalescent plasma) to treat COVID19. This was also a popular question from our weekly roundup, *and* it’s been Read more…
Hydroxychloroquine – yay or nay?
Treatments Uncertainty and Misinformation
Lindsey Leininger, PhD MA
A: The best evidence (still) suggests a resounding nay. ***** EDITED: 11:44 am to include FDA evidence review in the reference section ******* For our TGIF post we’re going to revisit the hydroxychloroquine (HCQ) debate, because let’s get real, friends…..it’s been quite the week on the HCQ information frontlines. We Nerdy Girls are here to Read more…
July 6, 2020
HYDROXYCHLOROQUINE FOR HOSPITALIZED COVID PATIENTS?
Treatments Uncertainty and Misinformation
Lindsey Leininger, PhD MA
THE DATA (STILL) SUGGEST “NO” New data out of the Detroit area find that hospitalized COVID patients receiving hydroxychloroquine (HCQ) were less likely to die than those not receiving the drug. Sensational headlines ensued. The scientific community sighed in disappointment and frustration. Why? (1) Administration of HCQ was NOT RANDOMIZED (2) The HCQ and non-HCQ Read more…
July 5, 2020
What have we learned about treatment of Covid-19 to date?
Treatments
Ashley Ritter, APRN, PhD
A: New discoveries happen every day! In addition to research taking place to develop a vaccine, many clinicians and researchers are learning more about how to treat Covid-19 infection. The new knowledge about treatment falls into three categories: 1) pathophysiology of Covid-19 infection, 2) decreasing disease severity, and 3) minimizing long-term complications. Understanding the physiologic Read more…
June 24, 2020
How do I make sense of all of the treatments being tested in clinical trials?! I can’t keep up – anti-virals, anti-inflammatories, antibodies….OH MY.
Treatments
Lindsey Leininger, PhD MA
A: What a confusing jumble! We Nerdy Girls like to keep the following phrase in mind: TREATMENT TIMING MATTERS. Different treatments target different points in the disease course, as helpfully demonstrated in these figures. Punchline: We’ll need an entire bag of treatment tricks to beat this devilishly nasty disease. A little more context: First we Read more…
June 18, 2020
Can you tell me the story of Hydroxychloroquine again?
Treatments Uncertainty and Misinformation
Aparna Kumar, PhD CRNP MPH
A: Absolutely. To answer this question, we turn to the analysis of others….because we also love elevating others’ excellent and succinct work for you. This quick video by The Incidental Economist hits on the major points of the retracted studies and where we are now. It also ends on a hopeful message: “Science isn’t perfect. Read more…
June 16, 2020
Study On Use of Steroids to Reduce COVID-19 Deaths
Treatments
Lindsey Leininger, PhD MA
BREAKING NEWS: A well-designed study by a respectable research group has yielded preliminary results indicating that a common, inexpensive steroid reduced deaths among very ill patients hospitalized with COVID-19. Nerdy Girl initial reactions: (1) THE STUDY IS WELL-DESIGNED Using the 3 Cs Framework: COMPARISON, CHANCE, and CONTEXT a) There is a randomly assigned COMPARISON group Read more…
A: The best evidence (still) suggests a resounding nay. ***** EDITED: 11:44 am to include FDA evidence review in the reference section ******* For our TGIF post we’re going to revisit the hydroxychloroquine (HCQ) debate, because let’s get real, friends…..it’s been quite the week on the HCQ information frontlines. We Nerdy Girls are here to Read more…
HYDROXYCHLOROQUINE FOR HOSPITALIZED COVID PATIENTS?
Treatments Uncertainty and Misinformation
Lindsey Leininger, PhD MA
THE DATA (STILL) SUGGEST “NO” New data out of the Detroit area find that hospitalized COVID patients receiving hydroxychloroquine (HCQ) were less likely to die than those not receiving the drug. Sensational headlines ensued. The scientific community sighed in disappointment and frustration. Why? (1) Administration of HCQ was NOT RANDOMIZED (2) The HCQ and non-HCQ Read more…
July 5, 2020
What have we learned about treatment of Covid-19 to date?
Treatments
Ashley Ritter, APRN, PhD
A: New discoveries happen every day! In addition to research taking place to develop a vaccine, many clinicians and researchers are learning more about how to treat Covid-19 infection. The new knowledge about treatment falls into three categories: 1) pathophysiology of Covid-19 infection, 2) decreasing disease severity, and 3) minimizing long-term complications. Understanding the physiologic Read more…
June 24, 2020
How do I make sense of all of the treatments being tested in clinical trials?! I can’t keep up – anti-virals, anti-inflammatories, antibodies….OH MY.
Treatments
Lindsey Leininger, PhD MA
A: What a confusing jumble! We Nerdy Girls like to keep the following phrase in mind: TREATMENT TIMING MATTERS. Different treatments target different points in the disease course, as helpfully demonstrated in these figures. Punchline: We’ll need an entire bag of treatment tricks to beat this devilishly nasty disease. A little more context: First we Read more…
June 18, 2020
Can you tell me the story of Hydroxychloroquine again?
Treatments Uncertainty and Misinformation
Aparna Kumar, PhD CRNP MPH
A: Absolutely. To answer this question, we turn to the analysis of others….because we also love elevating others’ excellent and succinct work for you. This quick video by The Incidental Economist hits on the major points of the retracted studies and where we are now. It also ends on a hopeful message: “Science isn’t perfect. Read more…
June 16, 2020
Study On Use of Steroids to Reduce COVID-19 Deaths
Treatments
Lindsey Leininger, PhD MA
BREAKING NEWS: A well-designed study by a respectable research group has yielded preliminary results indicating that a common, inexpensive steroid reduced deaths among very ill patients hospitalized with COVID-19. Nerdy Girl initial reactions: (1) THE STUDY IS WELL-DESIGNED Using the 3 Cs Framework: COMPARISON, CHANCE, and CONTEXT a) There is a randomly assigned COMPARISON group Read more…
THE DATA (STILL) SUGGEST “NO” New data out of the Detroit area find that hospitalized COVID patients receiving hydroxychloroquine (HCQ) were less likely to die than those not receiving the drug. Sensational headlines ensued. The scientific community sighed in disappointment and frustration. Why? (1) Administration of HCQ was NOT RANDOMIZED (2) The HCQ and non-HCQ Read more…
What have we learned about treatment of Covid-19 to date?
Treatments
Ashley Ritter, APRN, PhD
A: New discoveries happen every day! In addition to research taking place to develop a vaccine, many clinicians and researchers are learning more about how to treat Covid-19 infection. The new knowledge about treatment falls into three categories: 1) pathophysiology of Covid-19 infection, 2) decreasing disease severity, and 3) minimizing long-term complications. Understanding the physiologic Read more…
June 24, 2020
How do I make sense of all of the treatments being tested in clinical trials?! I can’t keep up – anti-virals, anti-inflammatories, antibodies….OH MY.
Treatments
Lindsey Leininger, PhD MA
A: What a confusing jumble! We Nerdy Girls like to keep the following phrase in mind: TREATMENT TIMING MATTERS. Different treatments target different points in the disease course, as helpfully demonstrated in these figures. Punchline: We’ll need an entire bag of treatment tricks to beat this devilishly nasty disease. A little more context: First we Read more…
June 18, 2020
Can you tell me the story of Hydroxychloroquine again?
Treatments Uncertainty and Misinformation
Aparna Kumar, PhD CRNP MPH
A: Absolutely. To answer this question, we turn to the analysis of others….because we also love elevating others’ excellent and succinct work for you. This quick video by The Incidental Economist hits on the major points of the retracted studies and where we are now. It also ends on a hopeful message: “Science isn’t perfect. Read more…
June 16, 2020
Study On Use of Steroids to Reduce COVID-19 Deaths
Treatments
Lindsey Leininger, PhD MA
BREAKING NEWS: A well-designed study by a respectable research group has yielded preliminary results indicating that a common, inexpensive steroid reduced deaths among very ill patients hospitalized with COVID-19. Nerdy Girl initial reactions: (1) THE STUDY IS WELL-DESIGNED Using the 3 Cs Framework: COMPARISON, CHANCE, and CONTEXT a) There is a randomly assigned COMPARISON group Read more…
A: New discoveries happen every day! In addition to research taking place to develop a vaccine, many clinicians and researchers are learning more about how to treat Covid-19 infection. The new knowledge about treatment falls into three categories: 1) pathophysiology of Covid-19 infection, 2) decreasing disease severity, and 3) minimizing long-term complications. Understanding the physiologic Read more…
How do I make sense of all of the treatments being tested in clinical trials?! I can’t keep up – anti-virals, anti-inflammatories, antibodies….OH MY.
Treatments
Lindsey Leininger, PhD MA
A: What a confusing jumble! We Nerdy Girls like to keep the following phrase in mind: TREATMENT TIMING MATTERS. Different treatments target different points in the disease course, as helpfully demonstrated in these figures. Punchline: We’ll need an entire bag of treatment tricks to beat this devilishly nasty disease. A little more context: First we Read more…
June 18, 2020
Can you tell me the story of Hydroxychloroquine again?
Treatments Uncertainty and Misinformation
Aparna Kumar, PhD CRNP MPH
A: Absolutely. To answer this question, we turn to the analysis of others….because we also love elevating others’ excellent and succinct work for you. This quick video by The Incidental Economist hits on the major points of the retracted studies and where we are now. It also ends on a hopeful message: “Science isn’t perfect. Read more…
June 16, 2020
Study On Use of Steroids to Reduce COVID-19 Deaths
Treatments
Lindsey Leininger, PhD MA
BREAKING NEWS: A well-designed study by a respectable research group has yielded preliminary results indicating that a common, inexpensive steroid reduced deaths among very ill patients hospitalized with COVID-19. Nerdy Girl initial reactions: (1) THE STUDY IS WELL-DESIGNED Using the 3 Cs Framework: COMPARISON, CHANCE, and CONTEXT a) There is a randomly assigned COMPARISON group Read more…
A: What a confusing jumble! We Nerdy Girls like to keep the following phrase in mind: TREATMENT TIMING MATTERS. Different treatments target different points in the disease course, as helpfully demonstrated in these figures. Punchline: We’ll need an entire bag of treatment tricks to beat this devilishly nasty disease. A little more context: First we Read more…
Can you tell me the story of Hydroxychloroquine again?
Treatments Uncertainty and Misinformation
Aparna Kumar, PhD CRNP MPH
A: Absolutely. To answer this question, we turn to the analysis of others….because we also love elevating others’ excellent and succinct work for you. This quick video by The Incidental Economist hits on the major points of the retracted studies and where we are now. It also ends on a hopeful message: “Science isn’t perfect. Read more…
June 16, 2020
Study On Use of Steroids to Reduce COVID-19 Deaths
Treatments
Lindsey Leininger, PhD MA
BREAKING NEWS: A well-designed study by a respectable research group has yielded preliminary results indicating that a common, inexpensive steroid reduced deaths among very ill patients hospitalized with COVID-19. Nerdy Girl initial reactions: (1) THE STUDY IS WELL-DESIGNED Using the 3 Cs Framework: COMPARISON, CHANCE, and CONTEXT a) There is a randomly assigned COMPARISON group Read more…
A: Absolutely. To answer this question, we turn to the analysis of others….because we also love elevating others’ excellent and succinct work for you. This quick video by The Incidental Economist hits on the major points of the retracted studies and where we are now. It also ends on a hopeful message: “Science isn’t perfect. Read more…
Study On Use of Steroids to Reduce COVID-19 Deaths
Treatments
Lindsey Leininger, PhD MA
BREAKING NEWS: A well-designed study by a respectable research group has yielded preliminary results indicating that a common, inexpensive steroid reduced deaths among very ill patients hospitalized with COVID-19. Nerdy Girl initial reactions: (1) THE STUDY IS WELL-DESIGNED Using the 3 Cs Framework: COMPARISON, CHANCE, and CONTEXT a) There is a randomly assigned COMPARISON group Read more…
BREAKING NEWS: A well-designed study by a respectable research group has yielded preliminary results indicating that a common, inexpensive steroid reduced deaths among very ill patients hospitalized with COVID-19. Nerdy Girl initial reactions: (1) THE STUDY IS WELL-DESIGNED Using the 3 Cs Framework: COMPARISON, CHANCE, and CONTEXT a) There is a randomly assigned COMPARISON group Read more…

