Posts from Those Nerdy Girls

All the posts from our Those Nerdy Girls Facebook page dating back to May 1st, 2020, are currently archived here and can be searched for by category, key words, etc. Be sure to check back often as additional posts are being added each day.

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Should those who have had COVID-19 and recovered be issued an “immunity passport” or “risk-free certificate”?

Biology/Immunity Infection and Spread

A: The World Health Organization states, “At this point in the pandemic, there is not enough evidence about the effectiveness of antibody-mediated immunity to guarantee the accuracy of an “immunity passport” or “risk-free certificate.”” Main reasons why: Laboratory tests that detect antibodies to SARS-CoV-2 in people need further validation to determine their accuracy and reliability Read more…

Are there neurological issues, other than strokes, that I should worry about?

Biology/Immunity Clinical Symptoms

A: Yes and no. Most of the other neurological complications seen to date have occurred later in disease progression (some time after active COVID-19 symptoms). There is some concern that COVID-19 can have effects on neural cells in the brain through the same mechanism that the virus enters other cells (ACE-2 receptor). There is also Read more…

I have been hearing about young, healthy people who didn’t have overt symptoms of COVID-19 having strokes. What does this mean?

Biology/Immunity Clinical Symptoms

A: We are still learning a great deal about the virus. Early reports from Italy and China have demonstrated that patients positive for COVID-19 are at an increased risk of developing blood clots, which can increase the risk of stroke due to occlusion of the blood vessels (1). Increasing cases of young, otherwise healthy people Read more…

Could over 20% of individuals living in New York City really already have been exposed to COVID-19?

Biology/Immunity Infection and Spread

A: Possibly, but there are a few things to consider about the sample of individuals included in the study (and all sero-surveys assessing past exposure to the infection via detection of antibodies targeted against SARS-CoV-2). In this study, ~3000 individuals (~1300 in NYC specifically) were recruited to be tested for presence of antibodies targeted against Read more…

I keep hearing reports that a lab accident caused the pandemic. Is this true?

Infection and Spread Uncertainty and Misinformation

A: Experts agree: “Virtually no chance.” NPR canvassed ten leading researchers specializing in coronaviruses and/or lab accidents, all of whom share the view that this virus was first transmitted to humans by animals in a real-world setting. As Robert Garry, a microbiologist at Tulane, goes on to explain: “The virus is really too good at Read more…

I’m young(ish) and healthy, do I really need to worry about catching COVID-19?

Clinical Symptoms Infection and Spread

A: While the most serious risk for complications and mortality is still at older ages and those with co-morbidities, the course of disease in younger and middle-aged adults is proving highly unpredictable. “There’s a big difference in how people handle this virus,” says Robert Murphy, a professor of medicine and the director of the Center Read more…

I know I’ve been infected with COVID-19. How long am I contagious for and when can I come out of isolation?

Infection and Spread Staying Safe

A. Scientists still don’t know how long people remain contagious for after infection. The CDC has issued guidelines for when people with known COVID infection can leave the house for essential trips: No fever for at least 72 hours without the use of medicines to reduce the fever, AND Other symptoms have improved, AND At Read more…

I’ve been seeing a therapist for several years and we recently moved to facetime appointments. It just doesn’t feel right. Should we break up?

Mental Health

A: We are all adjusting right now. And therapists, psychiatrists, social workers, counselors, and others who provide mental health services are more often than not working virtually. One thing to keep in mind: Even if it feels different, research has shown that telemental health services can be just as effective as in person services. And Read more…

What things should I consider if I want to move my loved one out of a nursing home or assisted living facility during the current pandemic?

Families/Kids Infection and Spread Staying Safe

A: Several factors make COVID-19 very dangerous to nursing home and assisted living residents. The virus can go undetected in staff and residents with no symptoms, facilitating rapid spread to older adults with underlying health conditions and their vital care providers. Like hospitals, adequate protective equipment and the capacity to test residents and staff are Read more…

I’ve been hearing a lot about false negative COVID test results. Can you explain?

Data and Metrics Testing and Contact Tracing

A: The false negative rate is the % of infected individuals who incorrectly test negative for COVID. For example, a hot-off-the-press NPR article reports a 15% false negative rate for Abbott’s new rapid COVID test. A 15% false negative rate indicates that out of 100 infected individuals, 15 would incorrectly test negative. How do we Read more…

I now know a little more about serological testing and antibodies. But I still have questions. For example, I read about antibody studies in California that say as many as 4% of all people have had the coronavirus. What does this mean?

Testing and Contact Tracing

A: The short answer, as statistician Thomas Lumley says, is that “counting rare things is hard.” There is much we still don’t know about antibody testing for COVID-19 (levels of detection, interpretation, length/duration/extent of immunity). One issue is the testing itself. While current active illness tests (swab/PCR) are very accurate when performed correctly and at Read more…