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I need to know more about this virus. With all this talk about church choirs being risky events, does this imply that the virus is spread through the air?

Clinical Symptoms Infection and Spread

A: We still believe that the virus is transmitted primarily through droplets. But, here’s the truth: there is a very fine line between droplet and airborne transmission. Airborne: Transmitted by tiny droplets that remain suspended in the air. Can travel distances. (Hypothesized for SARS and MERS) Droplet: Transmitted by larger droplets that fall to the Read more…

I’m still confused about the difference between an INCUBATION period and an INFECTIOUS period.

Infection and Spread

Coronavirus 101 explainer, please!!! A: We empathize – there are so many terms to learn. For us, too! It’s literally impossible to be an expert on every dimension of the pandemic). This timeline courtesy of the Johns Hopkins School of Public Health helpfully visualizes the two concepts, along with how they link up chronologically. Here Read more…

Tell me more about convalescent plasma as a form of treatment for COVID-19. Does it really work? Can I donate antibodies to help others if I have recovered from COVID-19?

Treatments

A. Convalescent plasma is a treatment that’s more than a century old and has been previously used as treatment for other infectious diseases, including the 1918 Pandemic Flu, MERS, and the 2003 outbreak of SARS. It involves taking antibody-rich blood plasma from recovered, healthy donors, and transfusing it into patients with severe disease as a Read more…

How high a priority is it to get my kid to the pediatrician’s office for routine vaccines? Is it safe to go there?!?

Families/Kids Staying Safe

A: High priority. Super high. *Please* try to keep your kids up-to-date on their vaccination schedule. It’s better for them, and better for all, but there is evidence that coverage is slipping as parents skip or delay well-child visits. Wrapping up our weekend special series on kids + COVID with an up-close look at a Read more…

Should I just get it over with and go to a ‘COVID party’?

Biology/Immunity Infection and Spread Staying Safe

A: For the love of peanut butter and jelly, please NO, 1000 X NO! “Health officials in a county in southern Washington state say a rise in coronavirus cases is linked to “COVID-19 parties.” NBC News Link “Walla Walla County health officials are receiving reports of COVID-19 parties occurring in our community, where noninfected people Read more…

Is it morbid or wrong to start a conversation about end-of-life wishes with my family right now?

Families/Kids

A: NO! Now is a GREAT time to talk about end-of-life wishes with your inner circle. Talking about death can feel uncomfortable, but there are several benefits to doing this early and often. First, it’s really easy to misunderstand your family members’ wishes without a specific conversation. Opportunities to have conversations are better suited before Read more…

When comparing COVID-19 cases across countries, should I look at graphs that are adjusted for country population size or just the total number of cases?

Data and Metrics Data Literacy Infection and Spread

Q: If I want to look at graphs of COVID-19 cases and compare across countries, should I look at graphs that are adjusted for country population size (for example, number of cases per 100,000 people) or just the total number of cases? A: Hey, whatever floats your boat, we won’t judge, but there’s a good Read more…

Should those who have had COVID-19 and recovered be issued an “immunity passport” or “risk-free certificate”?

Biology/Immunity Infection and Spread

A: The World Health Organization states, “At this point in the pandemic, there is not enough evidence about the effectiveness of antibody-mediated immunity to guarantee the accuracy of an “immunity passport” or “risk-free certificate.”” Main reasons why: Laboratory tests that detect antibodies to SARS-CoV-2 in people need further validation to determine their accuracy and reliability Read more…

Could over 20% of individuals living in New York City really already have been exposed to COVID-19?

Biology/Immunity Infection and Spread

A: Possibly, but there are a few things to consider about the sample of individuals included in the study (and all sero-surveys assessing past exposure to the infection via detection of antibodies targeted against SARS-CoV-2). In this study, ~3000 individuals (~1300 in NYC specifically) were recruited to be tested for presence of antibodies targeted against Read more…

What things should I consider if I want to move my loved one out of a nursing home or assisted living facility during the current pandemic?

Families/Kids Infection and Spread Staying Safe

A: Several factors make COVID-19 very dangerous to nursing home and assisted living residents. The virus can go undetected in staff and residents with no symptoms, facilitating rapid spread to older adults with underlying health conditions and their vital care providers. Like hospitals, adequate protective equipment and the capacity to test residents and staff are Read more…

I’ve been hearing a lot about false negative COVID test results. Can you explain?

Data and Metrics Testing and Contact Tracing

A: The false negative rate is the % of infected individuals who incorrectly test negative for COVID. For example, a hot-off-the-press NPR article reports a 15% false negative rate for Abbott’s new rapid COVID test. A 15% false negative rate indicates that out of 100 infected individuals, 15 would incorrectly test negative. How do we Read more…

I now know a little more about serological testing and antibodies. But I still have questions. For example, I read about antibody studies in California that say as many as 4% of all people have had the coronavirus. What does this mean?

Testing and Contact Tracing

A: The short answer, as statistician Thomas Lumley says, is that “counting rare things is hard.” There is much we still don’t know about antibody testing for COVID-19 (levels of detection, interpretation, length/duration/extent of immunity). One issue is the testing itself. While current active illness tests (swab/PCR) are very accurate when performed correctly and at Read more…