What’s the best MASK to protect me from the Omicron variant?
COVID Variants MasksJennifer Beam Dowd, PhD
A: A well-fitted, high filtration mask such as N95, KN95, FFP2 or KF94. ⚠️ Omicron may be even more transmissible than previous variants, possibly due to faster replication in the upper airways, meaning people will expel lots of virus when breathing and talking. While vaccination is still your #1 defense against Omicron, it’s also a Read more…
December 21, 2021
Why should we get a booster with the existing COVID vaccine when a new one is in the works for Omicron?
COVID Variants Vaccines
Amanda Simanek, PhD MPH
A: Boosters with the original Pfizer and Moderna vaccines increase protection against the omicron variant…NOW. A few weeks ago we posted on results from Pfizer showing that: 🔵 A third dose of the original Pfizer vaccine increased neutralizing antibody titers against the omicron variant by 25-fold, compared to levels seen with only two doses 🔵 Read more…
December 20, 2021
Is it true that Omicron is less severe than previous variants?
COVID Variants
Jennifer Beam Dowd, PhD
A: We HOPE so, but we don’t know yet. The evidence so far is mixed. TL;DR We are WAY past due for some good variant news. But pinning our Omicron hopes on a less virulent variant is not wise for two reasons: 1) It might not be less severe in those who are “immune naïve” Read more…
December 16, 2021
POSTCARDS FROM THE UK: Buckle up America (and everywhere else).
COVID Variants Data and Metrics Infection and Spread
Jennifer Beam Dowd, PhD
And by buckle up, I mean BOOST-UP. And take other sensible precautions, especially leading up to the holidays. Nerdy Girl Jenn (🇺🇸 in 🇬🇧 ) writing from not-so-sunny England, home of the strangest shaped epidemic curve ever seen (Figure 1). Delta has been raging here since June and never went away. Omicron has a significant Read more…
December 14, 2021
How does one variant push out another? Why do two variants not take off at the same time in a country?
COVID Variants
Guest Author Jessica Williams-Nguyen, PhD
TL;DR: Great question! There are new variants emerging all the time. It’s a normal part of viral evolution. They compete by infecting people and making copies of themselves. Because of exponential math, even a small transmission advantage can quickly add up. This all goes back to evolution and math. Here’s how it works. A virus Read more…
December 13, 2021
Can our current COVID-19 diagnostics, like PCR tests and rapid antigen tests, detect the Omicron variant?
COVID Variants Testing and Contact Tracing
Chana Davis, PhD
A: Good news. Standard diagnostic PCR tests can pick up the Omicron variant. As far as we know, most rapid antigen tests can also detect Omicron, but tests are ongoing to determine if any specific brands are less sensitive to Omicron. Stay tuned! WHICH VARIANT DO I HAVE? 🦠 Standard diagnostic tests can’t tell you Read more…
December 11, 2021
I keep hearing all these new terms since the omicron variant came on the scene-can you clarify what all these words mean?
COVID Variants
Amanda Simanek, PhD MPH
A: Yes! Here are some explanations of many of the buzzwords flying 🦟 around right now….variant of concern, neutralizing antibodies, immune evasion and more! *Variant*: A variant is a version of the SARS-CoV-2 virus that has changes to its genetic sequence (i.e., mutations). These changes make it distinct from the other versions of the virus Read more…
December 8, 2021
OMICRON AND PFIZER/BIONTECH
COVID Variants Vaccines
Jennifer Beam Dowd, PhD
The trickle of Omicron data is quickly becoming a fountain ⛲. On the heels of yesterday’s Omicron studies, (see summary here) Pfizer today released data showing strong neutralization of Omicron after 3 doses of its vaccine, but a significant reduction for 2 doses. Highlights: ➡️ 2 doses showed significantly reduced neutralization titers against Omicron. ➡️ A Read more…
December 7, 2021
THIS JUST IN: Preliminary Omicron neutralizing antibody study
COVID Variants Vaccines
Jennifer Beam Dowd, PhD
⬇️ TL;DR: IN A LAB DISH (so NOT in real life), antibodies from vaccinated individuals (two doses of Pfizer-BioNTech), were significantly less effective at neutralizing Omicron compared to the original variant—about a 20-40-fold reduction in neutralization. While this is substantially more loss of neutralization than previous variants…this does NOT tell us how well the vaccines Read more…
December 7, 2021
Do COVID-19 vaccines promote the emergence of new variants?
COVID Variants Uncertainty and Misinformation Vaccines
Jennifer Beam Dowd, PhD
A: No. Vaccines REDUCE opportunities for viral replication needed for variants to emerge. Since the recent Omicron news, we are hearing this myth make the rounds again. ➡️ TL;DR: The virus has more opportunity to replicate in unvaccinated populations, creating a FAR bigger risk for the development of SARS-CoV-2 mutations. Even so, the good news Read more…
December 2, 2021
Are normal precautions (masks, distance, ventilation) less effective against new variants?
COVID Variants Staying Safe
Jennifer Beam Dowd, PhD
A: NOPE. Virus mutations STILL don’t defy the laws of physics. TL;DR: Whether Omicron or Delta, all SARS-CoV-2 variants are transmitted the same way, so you can reduce risk by using your #SMARTS: ↔️ Space: Keep your distance from other people. 😷 Masks: Keep your nose + mouth covered. 💨 Air: Keep it fresh. 🔄 Read more…
December 1, 2021
What’s new with Omicron?
COVID Variants Vaccines
Jennifer Beam Dowd, PhD
A: IT’S. STILL. TOO. SOON. TO. TELL. We know, the media panic level has been HIGH this week. But the truth is NO expert or TV pundit can predict what will happen with the new variant Omicron right now. We simply don’t have enough data yet on the key questions about the variant: 1) Is Read more…
November 27, 2021
Omicron – Blip or Blow-up?
COVID Variants Uncertainty and Misinformation
Lindsey Leininger, PhD MA
******UPDATE, 1:05 pm EST, 11/27/21: New cases are being reported in other countries. We can expect more of the same as surveillance goes into overdrive. I keep reminding myself that science doesn’t move at the speed of the news cycle. So we won’t know for a while which details are signal and which are noise. Read more…
October 6, 2021
What’s the best MASK to protect me from the Delta variant?
COVID Variants Masks
Jennifer Beam Dowd, PhD
A: A well-fitted, high filtration mask such as N95, KN95, FFP2 or KF94. ⚠️ Delta is more transmissible, in part due to infected people shedding more virus from their nose and mouth. While vaccination is still your #1 defense against Delta, it’s also a good idea to UPGRADE YOUR MASK when you are in higher Read more…
October 5, 2021
When can we expect a variant specific (i.e. Delta variant) booster shot?
COVID Variants Vaccines
Amanda Simanek, PhD MPH
A: Variant specific boosters are currently being tested, but it’s not clear whether we need them just yet. Here is a run-down of ongoing trials: Pfizer/BioNTech has two Phase 2/3 trials ongoing, one with a booster designed to target the Beta variant (the one that emerged in South Africa in late 2020) and one that Read more…
September 2, 2021
California Classroom Outbreak Explained
COVID Variants Infection and Spread School
Jennifer Beam Dowd, PhD
A recent CDC outbreak investigation found that an unvaccinated teacher infected twelve elementary school students out of a class of 24 students in California. All students were too young to be eligible for the vaccine. Key take-aways: ➡️ GET VACCINATED ➡️ KEEP YOUR MASK ON WHILE TALKING!! ➡️ STAY HOME WHEN SICK ➡️ GET VACCINATED Read more…
August 31, 2021
What’s going on with the Delta variant in the UK 🇬🇧? I heard cases were falling?
COVID Variants Data and Metrics
Jennifer Beam Dowd, PhD
A: It’s a mixed bag—cases *have* fallen from their peak but have now plateaued at a high level. TL;DR: ➡️ Cases remain stuck at a high level in the UK, despite high vaccination rates (higher than the US). This speaks to the transmissibility of Delta and means things could get worse in the US. ➡️ Read more…
August 26, 2021
How and why do viruses mutate?
Biology/Immunity COVID Variants Vaccines
Vijaya Knight, MD PhD (D)ABMLI
Q: What does this mean for future SARS-CoV-2 variants? A: After infection, the virus makes lots of copies of itself in the body which can lead to random changes (like typos) in the virus’ genetic code (mutations). While most mutations give no advantage to the virus, with enough chances for mutations, sometimes the virus hits Read more…
A: A well-fitted, high filtration mask such as N95, KN95, FFP2 or KF94. ⚠️ Omicron may be even more transmissible than previous variants, possibly due to faster replication in the upper airways, meaning people will expel lots of virus when breathing and talking. While vaccination is still your #1 defense against Omicron, it’s also a Read more…
Why should we get a booster with the existing COVID vaccine when a new one is in the works for Omicron?
COVID Variants VaccinesAmanda Simanek, PhD MPH
A: Boosters with the original Pfizer and Moderna vaccines increase protection against the omicron variant…NOW. A few weeks ago we posted on results from Pfizer showing that: 🔵 A third dose of the original Pfizer vaccine increased neutralizing antibody titers against the omicron variant by 25-fold, compared to levels seen with only two doses 🔵 Read more…
December 20, 2021
Is it true that Omicron is less severe than previous variants?
COVID Variants
Jennifer Beam Dowd, PhD
A: We HOPE so, but we don’t know yet. The evidence so far is mixed. TL;DR We are WAY past due for some good variant news. But pinning our Omicron hopes on a less virulent variant is not wise for two reasons: 1) It might not be less severe in those who are “immune naïve” Read more…
December 16, 2021
POSTCARDS FROM THE UK: Buckle up America (and everywhere else).
COVID Variants Data and Metrics Infection and Spread
Jennifer Beam Dowd, PhD
And by buckle up, I mean BOOST-UP. And take other sensible precautions, especially leading up to the holidays. Nerdy Girl Jenn (🇺🇸 in 🇬🇧 ) writing from not-so-sunny England, home of the strangest shaped epidemic curve ever seen (Figure 1). Delta has been raging here since June and never went away. Omicron has a significant Read more…
December 14, 2021
How does one variant push out another? Why do two variants not take off at the same time in a country?
COVID Variants
Guest Author Jessica Williams-Nguyen, PhD
TL;DR: Great question! There are new variants emerging all the time. It’s a normal part of viral evolution. They compete by infecting people and making copies of themselves. Because of exponential math, even a small transmission advantage can quickly add up. This all goes back to evolution and math. Here’s how it works. A virus Read more…
December 13, 2021
Can our current COVID-19 diagnostics, like PCR tests and rapid antigen tests, detect the Omicron variant?
COVID Variants Testing and Contact Tracing
Chana Davis, PhD
A: Good news. Standard diagnostic PCR tests can pick up the Omicron variant. As far as we know, most rapid antigen tests can also detect Omicron, but tests are ongoing to determine if any specific brands are less sensitive to Omicron. Stay tuned! WHICH VARIANT DO I HAVE? 🦠 Standard diagnostic tests can’t tell you Read more…
December 11, 2021
I keep hearing all these new terms since the omicron variant came on the scene-can you clarify what all these words mean?
COVID Variants
Amanda Simanek, PhD MPH
A: Yes! Here are some explanations of many of the buzzwords flying 🦟 around right now….variant of concern, neutralizing antibodies, immune evasion and more! *Variant*: A variant is a version of the SARS-CoV-2 virus that has changes to its genetic sequence (i.e., mutations). These changes make it distinct from the other versions of the virus Read more…
December 8, 2021
OMICRON AND PFIZER/BIONTECH
COVID Variants Vaccines
Jennifer Beam Dowd, PhD
The trickle of Omicron data is quickly becoming a fountain ⛲. On the heels of yesterday’s Omicron studies, (see summary here) Pfizer today released data showing strong neutralization of Omicron after 3 doses of its vaccine, but a significant reduction for 2 doses. Highlights: ➡️ 2 doses showed significantly reduced neutralization titers against Omicron. ➡️ A Read more…
December 7, 2021
THIS JUST IN: Preliminary Omicron neutralizing antibody study
COVID Variants Vaccines
Jennifer Beam Dowd, PhD
⬇️ TL;DR: IN A LAB DISH (so NOT in real life), antibodies from vaccinated individuals (two doses of Pfizer-BioNTech), were significantly less effective at neutralizing Omicron compared to the original variant—about a 20-40-fold reduction in neutralization. While this is substantially more loss of neutralization than previous variants…this does NOT tell us how well the vaccines Read more…
December 7, 2021
Do COVID-19 vaccines promote the emergence of new variants?
COVID Variants Uncertainty and Misinformation Vaccines
Jennifer Beam Dowd, PhD
A: No. Vaccines REDUCE opportunities for viral replication needed for variants to emerge. Since the recent Omicron news, we are hearing this myth make the rounds again. ➡️ TL;DR: The virus has more opportunity to replicate in unvaccinated populations, creating a FAR bigger risk for the development of SARS-CoV-2 mutations. Even so, the good news Read more…
December 2, 2021
Are normal precautions (masks, distance, ventilation) less effective against new variants?
COVID Variants Staying Safe
Jennifer Beam Dowd, PhD
A: NOPE. Virus mutations STILL don’t defy the laws of physics. TL;DR: Whether Omicron or Delta, all SARS-CoV-2 variants are transmitted the same way, so you can reduce risk by using your #SMARTS: ↔️ Space: Keep your distance from other people. 😷 Masks: Keep your nose + mouth covered. 💨 Air: Keep it fresh. 🔄 Read more…
December 1, 2021
What’s new with Omicron?
COVID Variants Vaccines
Jennifer Beam Dowd, PhD
A: IT’S. STILL. TOO. SOON. TO. TELL. We know, the media panic level has been HIGH this week. But the truth is NO expert or TV pundit can predict what will happen with the new variant Omicron right now. We simply don’t have enough data yet on the key questions about the variant: 1) Is Read more…
November 27, 2021
Omicron – Blip or Blow-up?
COVID Variants Uncertainty and Misinformation
Lindsey Leininger, PhD MA
******UPDATE, 1:05 pm EST, 11/27/21: New cases are being reported in other countries. We can expect more of the same as surveillance goes into overdrive. I keep reminding myself that science doesn’t move at the speed of the news cycle. So we won’t know for a while which details are signal and which are noise. Read more…
October 6, 2021
What’s the best MASK to protect me from the Delta variant?
COVID Variants Masks
Jennifer Beam Dowd, PhD
A: A well-fitted, high filtration mask such as N95, KN95, FFP2 or KF94. ⚠️ Delta is more transmissible, in part due to infected people shedding more virus from their nose and mouth. While vaccination is still your #1 defense against Delta, it’s also a good idea to UPGRADE YOUR MASK when you are in higher Read more…
October 5, 2021
When can we expect a variant specific (i.e. Delta variant) booster shot?
COVID Variants Vaccines
Amanda Simanek, PhD MPH
A: Variant specific boosters are currently being tested, but it’s not clear whether we need them just yet. Here is a run-down of ongoing trials: Pfizer/BioNTech has two Phase 2/3 trials ongoing, one with a booster designed to target the Beta variant (the one that emerged in South Africa in late 2020) and one that Read more…
September 2, 2021
California Classroom Outbreak Explained
COVID Variants Infection and Spread School
Jennifer Beam Dowd, PhD
A recent CDC outbreak investigation found that an unvaccinated teacher infected twelve elementary school students out of a class of 24 students in California. All students were too young to be eligible for the vaccine. Key take-aways: ➡️ GET VACCINATED ➡️ KEEP YOUR MASK ON WHILE TALKING!! ➡️ STAY HOME WHEN SICK ➡️ GET VACCINATED Read more…
August 31, 2021
What’s going on with the Delta variant in the UK 🇬🇧? I heard cases were falling?
COVID Variants Data and Metrics
Jennifer Beam Dowd, PhD
A: It’s a mixed bag—cases *have* fallen from their peak but have now plateaued at a high level. TL;DR: ➡️ Cases remain stuck at a high level in the UK, despite high vaccination rates (higher than the US). This speaks to the transmissibility of Delta and means things could get worse in the US. ➡️ Read more…
August 26, 2021
How and why do viruses mutate?
Biology/Immunity COVID Variants Vaccines
Vijaya Knight, MD PhD (D)ABMLI
Q: What does this mean for future SARS-CoV-2 variants? A: After infection, the virus makes lots of copies of itself in the body which can lead to random changes (like typos) in the virus’ genetic code (mutations). While most mutations give no advantage to the virus, with enough chances for mutations, sometimes the virus hits Read more…
A: Boosters with the original Pfizer and Moderna vaccines increase protection against the omicron variant…NOW. A few weeks ago we posted on results from Pfizer showing that: 🔵 A third dose of the original Pfizer vaccine increased neutralizing antibody titers against the omicron variant by 25-fold, compared to levels seen with only two doses 🔵 Read more…
Is it true that Omicron is less severe than previous variants?
COVID VariantsJennifer Beam Dowd, PhD
A: We HOPE so, but we don’t know yet. The evidence so far is mixed. TL;DR We are WAY past due for some good variant news. But pinning our Omicron hopes on a less virulent variant is not wise for two reasons: 1) It might not be less severe in those who are “immune naïve” Read more…
December 16, 2021
POSTCARDS FROM THE UK: Buckle up America (and everywhere else).
COVID Variants Data and Metrics Infection and Spread
Jennifer Beam Dowd, PhD
And by buckle up, I mean BOOST-UP. And take other sensible precautions, especially leading up to the holidays. Nerdy Girl Jenn (🇺🇸 in 🇬🇧 ) writing from not-so-sunny England, home of the strangest shaped epidemic curve ever seen (Figure 1). Delta has been raging here since June and never went away. Omicron has a significant Read more…
December 14, 2021
How does one variant push out another? Why do two variants not take off at the same time in a country?
COVID Variants
Guest Author Jessica Williams-Nguyen, PhD
TL;DR: Great question! There are new variants emerging all the time. It’s a normal part of viral evolution. They compete by infecting people and making copies of themselves. Because of exponential math, even a small transmission advantage can quickly add up. This all goes back to evolution and math. Here’s how it works. A virus Read more…
December 13, 2021
Can our current COVID-19 diagnostics, like PCR tests and rapid antigen tests, detect the Omicron variant?
COVID Variants Testing and Contact Tracing
Chana Davis, PhD
A: Good news. Standard diagnostic PCR tests can pick up the Omicron variant. As far as we know, most rapid antigen tests can also detect Omicron, but tests are ongoing to determine if any specific brands are less sensitive to Omicron. Stay tuned! WHICH VARIANT DO I HAVE? 🦠 Standard diagnostic tests can’t tell you Read more…
December 11, 2021
I keep hearing all these new terms since the omicron variant came on the scene-can you clarify what all these words mean?
COVID Variants
Amanda Simanek, PhD MPH
A: Yes! Here are some explanations of many of the buzzwords flying 🦟 around right now….variant of concern, neutralizing antibodies, immune evasion and more! *Variant*: A variant is a version of the SARS-CoV-2 virus that has changes to its genetic sequence (i.e., mutations). These changes make it distinct from the other versions of the virus Read more…
December 8, 2021
OMICRON AND PFIZER/BIONTECH
COVID Variants Vaccines
Jennifer Beam Dowd, PhD
The trickle of Omicron data is quickly becoming a fountain ⛲. On the heels of yesterday’s Omicron studies, (see summary here) Pfizer today released data showing strong neutralization of Omicron after 3 doses of its vaccine, but a significant reduction for 2 doses. Highlights: ➡️ 2 doses showed significantly reduced neutralization titers against Omicron. ➡️ A Read more…
December 7, 2021
THIS JUST IN: Preliminary Omicron neutralizing antibody study
COVID Variants Vaccines
Jennifer Beam Dowd, PhD
⬇️ TL;DR: IN A LAB DISH (so NOT in real life), antibodies from vaccinated individuals (two doses of Pfizer-BioNTech), were significantly less effective at neutralizing Omicron compared to the original variant—about a 20-40-fold reduction in neutralization. While this is substantially more loss of neutralization than previous variants…this does NOT tell us how well the vaccines Read more…
December 7, 2021
Do COVID-19 vaccines promote the emergence of new variants?
COVID Variants Uncertainty and Misinformation Vaccines
Jennifer Beam Dowd, PhD
A: No. Vaccines REDUCE opportunities for viral replication needed for variants to emerge. Since the recent Omicron news, we are hearing this myth make the rounds again. ➡️ TL;DR: The virus has more opportunity to replicate in unvaccinated populations, creating a FAR bigger risk for the development of SARS-CoV-2 mutations. Even so, the good news Read more…
December 2, 2021
Are normal precautions (masks, distance, ventilation) less effective against new variants?
COVID Variants Staying Safe
Jennifer Beam Dowd, PhD
A: NOPE. Virus mutations STILL don’t defy the laws of physics. TL;DR: Whether Omicron or Delta, all SARS-CoV-2 variants are transmitted the same way, so you can reduce risk by using your #SMARTS: ↔️ Space: Keep your distance from other people. 😷 Masks: Keep your nose + mouth covered. 💨 Air: Keep it fresh. 🔄 Read more…
December 1, 2021
What’s new with Omicron?
COVID Variants Vaccines
Jennifer Beam Dowd, PhD
A: IT’S. STILL. TOO. SOON. TO. TELL. We know, the media panic level has been HIGH this week. But the truth is NO expert or TV pundit can predict what will happen with the new variant Omicron right now. We simply don’t have enough data yet on the key questions about the variant: 1) Is Read more…
November 27, 2021
Omicron – Blip or Blow-up?
COVID Variants Uncertainty and Misinformation
Lindsey Leininger, PhD MA
******UPDATE, 1:05 pm EST, 11/27/21: New cases are being reported in other countries. We can expect more of the same as surveillance goes into overdrive. I keep reminding myself that science doesn’t move at the speed of the news cycle. So we won’t know for a while which details are signal and which are noise. Read more…
October 6, 2021
What’s the best MASK to protect me from the Delta variant?
COVID Variants Masks
Jennifer Beam Dowd, PhD
A: A well-fitted, high filtration mask such as N95, KN95, FFP2 or KF94. ⚠️ Delta is more transmissible, in part due to infected people shedding more virus from their nose and mouth. While vaccination is still your #1 defense against Delta, it’s also a good idea to UPGRADE YOUR MASK when you are in higher Read more…
October 5, 2021
When can we expect a variant specific (i.e. Delta variant) booster shot?
COVID Variants Vaccines
Amanda Simanek, PhD MPH
A: Variant specific boosters are currently being tested, but it’s not clear whether we need them just yet. Here is a run-down of ongoing trials: Pfizer/BioNTech has two Phase 2/3 trials ongoing, one with a booster designed to target the Beta variant (the one that emerged in South Africa in late 2020) and one that Read more…
September 2, 2021
California Classroom Outbreak Explained
COVID Variants Infection and Spread School
Jennifer Beam Dowd, PhD
A recent CDC outbreak investigation found that an unvaccinated teacher infected twelve elementary school students out of a class of 24 students in California. All students were too young to be eligible for the vaccine. Key take-aways: ➡️ GET VACCINATED ➡️ KEEP YOUR MASK ON WHILE TALKING!! ➡️ STAY HOME WHEN SICK ➡️ GET VACCINATED Read more…
August 31, 2021
What’s going on with the Delta variant in the UK 🇬🇧? I heard cases were falling?
COVID Variants Data and Metrics
Jennifer Beam Dowd, PhD
A: It’s a mixed bag—cases *have* fallen from their peak but have now plateaued at a high level. TL;DR: ➡️ Cases remain stuck at a high level in the UK, despite high vaccination rates (higher than the US). This speaks to the transmissibility of Delta and means things could get worse in the US. ➡️ Read more…
August 26, 2021
How and why do viruses mutate?
Biology/Immunity COVID Variants Vaccines
Vijaya Knight, MD PhD (D)ABMLI
Q: What does this mean for future SARS-CoV-2 variants? A: After infection, the virus makes lots of copies of itself in the body which can lead to random changes (like typos) in the virus’ genetic code (mutations). While most mutations give no advantage to the virus, with enough chances for mutations, sometimes the virus hits Read more…
A: We HOPE so, but we don’t know yet. The evidence so far is mixed. TL;DR We are WAY past due for some good variant news. But pinning our Omicron hopes on a less virulent variant is not wise for two reasons: 1) It might not be less severe in those who are “immune naïve” Read more…
POSTCARDS FROM THE UK: Buckle up America (and everywhere else).
COVID Variants Data and Metrics Infection and SpreadJennifer Beam Dowd, PhD
And by buckle up, I mean BOOST-UP. And take other sensible precautions, especially leading up to the holidays. Nerdy Girl Jenn (🇺🇸 in 🇬🇧 ) writing from not-so-sunny England, home of the strangest shaped epidemic curve ever seen (Figure 1). Delta has been raging here since June and never went away. Omicron has a significant Read more…
December 14, 2021
How does one variant push out another? Why do two variants not take off at the same time in a country?
COVID Variants
Guest Author Jessica Williams-Nguyen, PhD
TL;DR: Great question! There are new variants emerging all the time. It’s a normal part of viral evolution. They compete by infecting people and making copies of themselves. Because of exponential math, even a small transmission advantage can quickly add up. This all goes back to evolution and math. Here’s how it works. A virus Read more…
December 13, 2021
Can our current COVID-19 diagnostics, like PCR tests and rapid antigen tests, detect the Omicron variant?
COVID Variants Testing and Contact Tracing
Chana Davis, PhD
A: Good news. Standard diagnostic PCR tests can pick up the Omicron variant. As far as we know, most rapid antigen tests can also detect Omicron, but tests are ongoing to determine if any specific brands are less sensitive to Omicron. Stay tuned! WHICH VARIANT DO I HAVE? 🦠 Standard diagnostic tests can’t tell you Read more…
December 11, 2021
I keep hearing all these new terms since the omicron variant came on the scene-can you clarify what all these words mean?
COVID Variants
Amanda Simanek, PhD MPH
A: Yes! Here are some explanations of many of the buzzwords flying 🦟 around right now….variant of concern, neutralizing antibodies, immune evasion and more! *Variant*: A variant is a version of the SARS-CoV-2 virus that has changes to its genetic sequence (i.e., mutations). These changes make it distinct from the other versions of the virus Read more…
December 8, 2021
OMICRON AND PFIZER/BIONTECH
COVID Variants Vaccines
Jennifer Beam Dowd, PhD
The trickle of Omicron data is quickly becoming a fountain ⛲. On the heels of yesterday’s Omicron studies, (see summary here) Pfizer today released data showing strong neutralization of Omicron after 3 doses of its vaccine, but a significant reduction for 2 doses. Highlights: ➡️ 2 doses showed significantly reduced neutralization titers against Omicron. ➡️ A Read more…
December 7, 2021
THIS JUST IN: Preliminary Omicron neutralizing antibody study
COVID Variants Vaccines
Jennifer Beam Dowd, PhD
⬇️ TL;DR: IN A LAB DISH (so NOT in real life), antibodies from vaccinated individuals (two doses of Pfizer-BioNTech), were significantly less effective at neutralizing Omicron compared to the original variant—about a 20-40-fold reduction in neutralization. While this is substantially more loss of neutralization than previous variants…this does NOT tell us how well the vaccines Read more…
December 7, 2021
Do COVID-19 vaccines promote the emergence of new variants?
COVID Variants Uncertainty and Misinformation Vaccines
Jennifer Beam Dowd, PhD
A: No. Vaccines REDUCE opportunities for viral replication needed for variants to emerge. Since the recent Omicron news, we are hearing this myth make the rounds again. ➡️ TL;DR: The virus has more opportunity to replicate in unvaccinated populations, creating a FAR bigger risk for the development of SARS-CoV-2 mutations. Even so, the good news Read more…
December 2, 2021
Are normal precautions (masks, distance, ventilation) less effective against new variants?
COVID Variants Staying Safe
Jennifer Beam Dowd, PhD
A: NOPE. Virus mutations STILL don’t defy the laws of physics. TL;DR: Whether Omicron or Delta, all SARS-CoV-2 variants are transmitted the same way, so you can reduce risk by using your #SMARTS: ↔️ Space: Keep your distance from other people. 😷 Masks: Keep your nose + mouth covered. 💨 Air: Keep it fresh. 🔄 Read more…
December 1, 2021
What’s new with Omicron?
COVID Variants Vaccines
Jennifer Beam Dowd, PhD
A: IT’S. STILL. TOO. SOON. TO. TELL. We know, the media panic level has been HIGH this week. But the truth is NO expert or TV pundit can predict what will happen with the new variant Omicron right now. We simply don’t have enough data yet on the key questions about the variant: 1) Is Read more…
November 27, 2021
Omicron – Blip or Blow-up?
COVID Variants Uncertainty and Misinformation
Lindsey Leininger, PhD MA
******UPDATE, 1:05 pm EST, 11/27/21: New cases are being reported in other countries. We can expect more of the same as surveillance goes into overdrive. I keep reminding myself that science doesn’t move at the speed of the news cycle. So we won’t know for a while which details are signal and which are noise. Read more…
October 6, 2021
What’s the best MASK to protect me from the Delta variant?
COVID Variants Masks
Jennifer Beam Dowd, PhD
A: A well-fitted, high filtration mask such as N95, KN95, FFP2 or KF94. ⚠️ Delta is more transmissible, in part due to infected people shedding more virus from their nose and mouth. While vaccination is still your #1 defense against Delta, it’s also a good idea to UPGRADE YOUR MASK when you are in higher Read more…
October 5, 2021
When can we expect a variant specific (i.e. Delta variant) booster shot?
COVID Variants Vaccines
Amanda Simanek, PhD MPH
A: Variant specific boosters are currently being tested, but it’s not clear whether we need them just yet. Here is a run-down of ongoing trials: Pfizer/BioNTech has two Phase 2/3 trials ongoing, one with a booster designed to target the Beta variant (the one that emerged in South Africa in late 2020) and one that Read more…
September 2, 2021
California Classroom Outbreak Explained
COVID Variants Infection and Spread School
Jennifer Beam Dowd, PhD
A recent CDC outbreak investigation found that an unvaccinated teacher infected twelve elementary school students out of a class of 24 students in California. All students were too young to be eligible for the vaccine. Key take-aways: ➡️ GET VACCINATED ➡️ KEEP YOUR MASK ON WHILE TALKING!! ➡️ STAY HOME WHEN SICK ➡️ GET VACCINATED Read more…
August 31, 2021
What’s going on with the Delta variant in the UK 🇬🇧? I heard cases were falling?
COVID Variants Data and Metrics
Jennifer Beam Dowd, PhD
A: It’s a mixed bag—cases *have* fallen from their peak but have now plateaued at a high level. TL;DR: ➡️ Cases remain stuck at a high level in the UK, despite high vaccination rates (higher than the US). This speaks to the transmissibility of Delta and means things could get worse in the US. ➡️ Read more…
August 26, 2021
How and why do viruses mutate?
Biology/Immunity COVID Variants Vaccines
Vijaya Knight, MD PhD (D)ABMLI
Q: What does this mean for future SARS-CoV-2 variants? A: After infection, the virus makes lots of copies of itself in the body which can lead to random changes (like typos) in the virus’ genetic code (mutations). While most mutations give no advantage to the virus, with enough chances for mutations, sometimes the virus hits Read more…
And by buckle up, I mean BOOST-UP. And take other sensible precautions, especially leading up to the holidays. Nerdy Girl Jenn (🇺🇸 in 🇬🇧 ) writing from not-so-sunny England, home of the strangest shaped epidemic curve ever seen (Figure 1). Delta has been raging here since June and never went away. Omicron has a significant Read more…
How does one variant push out another? Why do two variants not take off at the same time in a country?
COVID VariantsGuest Author Jessica Williams-Nguyen, PhD
TL;DR: Great question! There are new variants emerging all the time. It’s a normal part of viral evolution. They compete by infecting people and making copies of themselves. Because of exponential math, even a small transmission advantage can quickly add up. This all goes back to evolution and math. Here’s how it works. A virus Read more…
December 13, 2021
Can our current COVID-19 diagnostics, like PCR tests and rapid antigen tests, detect the Omicron variant?
COVID Variants Testing and Contact Tracing
Chana Davis, PhD
A: Good news. Standard diagnostic PCR tests can pick up the Omicron variant. As far as we know, most rapid antigen tests can also detect Omicron, but tests are ongoing to determine if any specific brands are less sensitive to Omicron. Stay tuned! WHICH VARIANT DO I HAVE? 🦠 Standard diagnostic tests can’t tell you Read more…
December 11, 2021
I keep hearing all these new terms since the omicron variant came on the scene-can you clarify what all these words mean?
COVID Variants
Amanda Simanek, PhD MPH
A: Yes! Here are some explanations of many of the buzzwords flying 🦟 around right now….variant of concern, neutralizing antibodies, immune evasion and more! *Variant*: A variant is a version of the SARS-CoV-2 virus that has changes to its genetic sequence (i.e., mutations). These changes make it distinct from the other versions of the virus Read more…
December 8, 2021
OMICRON AND PFIZER/BIONTECH
COVID Variants Vaccines
Jennifer Beam Dowd, PhD
The trickle of Omicron data is quickly becoming a fountain ⛲. On the heels of yesterday’s Omicron studies, (see summary here) Pfizer today released data showing strong neutralization of Omicron after 3 doses of its vaccine, but a significant reduction for 2 doses. Highlights: ➡️ 2 doses showed significantly reduced neutralization titers against Omicron. ➡️ A Read more…
December 7, 2021
THIS JUST IN: Preliminary Omicron neutralizing antibody study
COVID Variants Vaccines
Jennifer Beam Dowd, PhD
⬇️ TL;DR: IN A LAB DISH (so NOT in real life), antibodies from vaccinated individuals (two doses of Pfizer-BioNTech), were significantly less effective at neutralizing Omicron compared to the original variant—about a 20-40-fold reduction in neutralization. While this is substantially more loss of neutralization than previous variants…this does NOT tell us how well the vaccines Read more…
December 7, 2021
Do COVID-19 vaccines promote the emergence of new variants?
COVID Variants Uncertainty and Misinformation Vaccines
Jennifer Beam Dowd, PhD
A: No. Vaccines REDUCE opportunities for viral replication needed for variants to emerge. Since the recent Omicron news, we are hearing this myth make the rounds again. ➡️ TL;DR: The virus has more opportunity to replicate in unvaccinated populations, creating a FAR bigger risk for the development of SARS-CoV-2 mutations. Even so, the good news Read more…
December 2, 2021
Are normal precautions (masks, distance, ventilation) less effective against new variants?
COVID Variants Staying Safe
Jennifer Beam Dowd, PhD
A: NOPE. Virus mutations STILL don’t defy the laws of physics. TL;DR: Whether Omicron or Delta, all SARS-CoV-2 variants are transmitted the same way, so you can reduce risk by using your #SMARTS: ↔️ Space: Keep your distance from other people. 😷 Masks: Keep your nose + mouth covered. 💨 Air: Keep it fresh. 🔄 Read more…
December 1, 2021
What’s new with Omicron?
COVID Variants Vaccines
Jennifer Beam Dowd, PhD
A: IT’S. STILL. TOO. SOON. TO. TELL. We know, the media panic level has been HIGH this week. But the truth is NO expert or TV pundit can predict what will happen with the new variant Omicron right now. We simply don’t have enough data yet on the key questions about the variant: 1) Is Read more…
November 27, 2021
Omicron – Blip or Blow-up?
COVID Variants Uncertainty and Misinformation
Lindsey Leininger, PhD MA
******UPDATE, 1:05 pm EST, 11/27/21: New cases are being reported in other countries. We can expect more of the same as surveillance goes into overdrive. I keep reminding myself that science doesn’t move at the speed of the news cycle. So we won’t know for a while which details are signal and which are noise. Read more…
October 6, 2021
What’s the best MASK to protect me from the Delta variant?
COVID Variants Masks
Jennifer Beam Dowd, PhD
A: A well-fitted, high filtration mask such as N95, KN95, FFP2 or KF94. ⚠️ Delta is more transmissible, in part due to infected people shedding more virus from their nose and mouth. While vaccination is still your #1 defense against Delta, it’s also a good idea to UPGRADE YOUR MASK when you are in higher Read more…
October 5, 2021
When can we expect a variant specific (i.e. Delta variant) booster shot?
COVID Variants Vaccines
Amanda Simanek, PhD MPH
A: Variant specific boosters are currently being tested, but it’s not clear whether we need them just yet. Here is a run-down of ongoing trials: Pfizer/BioNTech has two Phase 2/3 trials ongoing, one with a booster designed to target the Beta variant (the one that emerged in South Africa in late 2020) and one that Read more…
September 2, 2021
California Classroom Outbreak Explained
COVID Variants Infection and Spread School
Jennifer Beam Dowd, PhD
A recent CDC outbreak investigation found that an unvaccinated teacher infected twelve elementary school students out of a class of 24 students in California. All students were too young to be eligible for the vaccine. Key take-aways: ➡️ GET VACCINATED ➡️ KEEP YOUR MASK ON WHILE TALKING!! ➡️ STAY HOME WHEN SICK ➡️ GET VACCINATED Read more…
August 31, 2021
What’s going on with the Delta variant in the UK 🇬🇧? I heard cases were falling?
COVID Variants Data and Metrics
Jennifer Beam Dowd, PhD
A: It’s a mixed bag—cases *have* fallen from their peak but have now plateaued at a high level. TL;DR: ➡️ Cases remain stuck at a high level in the UK, despite high vaccination rates (higher than the US). This speaks to the transmissibility of Delta and means things could get worse in the US. ➡️ Read more…
August 26, 2021
How and why do viruses mutate?
Biology/Immunity COVID Variants Vaccines
Vijaya Knight, MD PhD (D)ABMLI
Q: What does this mean for future SARS-CoV-2 variants? A: After infection, the virus makes lots of copies of itself in the body which can lead to random changes (like typos) in the virus’ genetic code (mutations). While most mutations give no advantage to the virus, with enough chances for mutations, sometimes the virus hits Read more…
TL;DR: Great question! There are new variants emerging all the time. It’s a normal part of viral evolution. They compete by infecting people and making copies of themselves. Because of exponential math, even a small transmission advantage can quickly add up. This all goes back to evolution and math. Here’s how it works. A virus Read more…
Can our current COVID-19 diagnostics, like PCR tests and rapid antigen tests, detect the Omicron variant?
COVID Variants Testing and Contact TracingChana Davis, PhD
A: Good news. Standard diagnostic PCR tests can pick up the Omicron variant. As far as we know, most rapid antigen tests can also detect Omicron, but tests are ongoing to determine if any specific brands are less sensitive to Omicron. Stay tuned! WHICH VARIANT DO I HAVE? 🦠 Standard diagnostic tests can’t tell you Read more…
December 11, 2021
I keep hearing all these new terms since the omicron variant came on the scene-can you clarify what all these words mean?
COVID Variants
Amanda Simanek, PhD MPH
A: Yes! Here are some explanations of many of the buzzwords flying 🦟 around right now….variant of concern, neutralizing antibodies, immune evasion and more! *Variant*: A variant is a version of the SARS-CoV-2 virus that has changes to its genetic sequence (i.e., mutations). These changes make it distinct from the other versions of the virus Read more…
December 8, 2021
OMICRON AND PFIZER/BIONTECH
COVID Variants Vaccines
Jennifer Beam Dowd, PhD
The trickle of Omicron data is quickly becoming a fountain ⛲. On the heels of yesterday’s Omicron studies, (see summary here) Pfizer today released data showing strong neutralization of Omicron after 3 doses of its vaccine, but a significant reduction for 2 doses. Highlights: ➡️ 2 doses showed significantly reduced neutralization titers against Omicron. ➡️ A Read more…
December 7, 2021
THIS JUST IN: Preliminary Omicron neutralizing antibody study
COVID Variants Vaccines
Jennifer Beam Dowd, PhD
⬇️ TL;DR: IN A LAB DISH (so NOT in real life), antibodies from vaccinated individuals (two doses of Pfizer-BioNTech), were significantly less effective at neutralizing Omicron compared to the original variant—about a 20-40-fold reduction in neutralization. While this is substantially more loss of neutralization than previous variants…this does NOT tell us how well the vaccines Read more…
December 7, 2021
Do COVID-19 vaccines promote the emergence of new variants?
COVID Variants Uncertainty and Misinformation Vaccines
Jennifer Beam Dowd, PhD
A: No. Vaccines REDUCE opportunities for viral replication needed for variants to emerge. Since the recent Omicron news, we are hearing this myth make the rounds again. ➡️ TL;DR: The virus has more opportunity to replicate in unvaccinated populations, creating a FAR bigger risk for the development of SARS-CoV-2 mutations. Even so, the good news Read more…
December 2, 2021
Are normal precautions (masks, distance, ventilation) less effective against new variants?
COVID Variants Staying Safe
Jennifer Beam Dowd, PhD
A: NOPE. Virus mutations STILL don’t defy the laws of physics. TL;DR: Whether Omicron or Delta, all SARS-CoV-2 variants are transmitted the same way, so you can reduce risk by using your #SMARTS: ↔️ Space: Keep your distance from other people. 😷 Masks: Keep your nose + mouth covered. 💨 Air: Keep it fresh. 🔄 Read more…
December 1, 2021
What’s new with Omicron?
COVID Variants Vaccines
Jennifer Beam Dowd, PhD
A: IT’S. STILL. TOO. SOON. TO. TELL. We know, the media panic level has been HIGH this week. But the truth is NO expert or TV pundit can predict what will happen with the new variant Omicron right now. We simply don’t have enough data yet on the key questions about the variant: 1) Is Read more…
November 27, 2021
Omicron – Blip or Blow-up?
COVID Variants Uncertainty and Misinformation
Lindsey Leininger, PhD MA
******UPDATE, 1:05 pm EST, 11/27/21: New cases are being reported in other countries. We can expect more of the same as surveillance goes into overdrive. I keep reminding myself that science doesn’t move at the speed of the news cycle. So we won’t know for a while which details are signal and which are noise. Read more…
October 6, 2021
What’s the best MASK to protect me from the Delta variant?
COVID Variants Masks
Jennifer Beam Dowd, PhD
A: A well-fitted, high filtration mask such as N95, KN95, FFP2 or KF94. ⚠️ Delta is more transmissible, in part due to infected people shedding more virus from their nose and mouth. While vaccination is still your #1 defense against Delta, it’s also a good idea to UPGRADE YOUR MASK when you are in higher Read more…
October 5, 2021
When can we expect a variant specific (i.e. Delta variant) booster shot?
COVID Variants Vaccines
Amanda Simanek, PhD MPH
A: Variant specific boosters are currently being tested, but it’s not clear whether we need them just yet. Here is a run-down of ongoing trials: Pfizer/BioNTech has two Phase 2/3 trials ongoing, one with a booster designed to target the Beta variant (the one that emerged in South Africa in late 2020) and one that Read more…
September 2, 2021
California Classroom Outbreak Explained
COVID Variants Infection and Spread School
Jennifer Beam Dowd, PhD
A recent CDC outbreak investigation found that an unvaccinated teacher infected twelve elementary school students out of a class of 24 students in California. All students were too young to be eligible for the vaccine. Key take-aways: ➡️ GET VACCINATED ➡️ KEEP YOUR MASK ON WHILE TALKING!! ➡️ STAY HOME WHEN SICK ➡️ GET VACCINATED Read more…
August 31, 2021
What’s going on with the Delta variant in the UK 🇬🇧? I heard cases were falling?
COVID Variants Data and Metrics
Jennifer Beam Dowd, PhD
A: It’s a mixed bag—cases *have* fallen from their peak but have now plateaued at a high level. TL;DR: ➡️ Cases remain stuck at a high level in the UK, despite high vaccination rates (higher than the US). This speaks to the transmissibility of Delta and means things could get worse in the US. ➡️ Read more…
August 26, 2021
How and why do viruses mutate?
Biology/Immunity COVID Variants Vaccines
Vijaya Knight, MD PhD (D)ABMLI
Q: What does this mean for future SARS-CoV-2 variants? A: After infection, the virus makes lots of copies of itself in the body which can lead to random changes (like typos) in the virus’ genetic code (mutations). While most mutations give no advantage to the virus, with enough chances for mutations, sometimes the virus hits Read more…
A: Good news. Standard diagnostic PCR tests can pick up the Omicron variant. As far as we know, most rapid antigen tests can also detect Omicron, but tests are ongoing to determine if any specific brands are less sensitive to Omicron. Stay tuned! WHICH VARIANT DO I HAVE? 🦠 Standard diagnostic tests can’t tell you Read more…
I keep hearing all these new terms since the omicron variant came on the scene-can you clarify what all these words mean?
COVID VariantsAmanda Simanek, PhD MPH
A: Yes! Here are some explanations of many of the buzzwords flying 🦟 around right now….variant of concern, neutralizing antibodies, immune evasion and more! *Variant*: A variant is a version of the SARS-CoV-2 virus that has changes to its genetic sequence (i.e., mutations). These changes make it distinct from the other versions of the virus Read more…
December 8, 2021
OMICRON AND PFIZER/BIONTECH
COVID Variants Vaccines
Jennifer Beam Dowd, PhD
The trickle of Omicron data is quickly becoming a fountain ⛲. On the heels of yesterday’s Omicron studies, (see summary here) Pfizer today released data showing strong neutralization of Omicron after 3 doses of its vaccine, but a significant reduction for 2 doses. Highlights: ➡️ 2 doses showed significantly reduced neutralization titers against Omicron. ➡️ A Read more…
December 7, 2021
THIS JUST IN: Preliminary Omicron neutralizing antibody study
COVID Variants Vaccines
Jennifer Beam Dowd, PhD
⬇️ TL;DR: IN A LAB DISH (so NOT in real life), antibodies from vaccinated individuals (two doses of Pfizer-BioNTech), were significantly less effective at neutralizing Omicron compared to the original variant—about a 20-40-fold reduction in neutralization. While this is substantially more loss of neutralization than previous variants…this does NOT tell us how well the vaccines Read more…
December 7, 2021
Do COVID-19 vaccines promote the emergence of new variants?
COVID Variants Uncertainty and Misinformation Vaccines
Jennifer Beam Dowd, PhD
A: No. Vaccines REDUCE opportunities for viral replication needed for variants to emerge. Since the recent Omicron news, we are hearing this myth make the rounds again. ➡️ TL;DR: The virus has more opportunity to replicate in unvaccinated populations, creating a FAR bigger risk for the development of SARS-CoV-2 mutations. Even so, the good news Read more…
December 2, 2021
Are normal precautions (masks, distance, ventilation) less effective against new variants?
COVID Variants Staying Safe
Jennifer Beam Dowd, PhD
A: NOPE. Virus mutations STILL don’t defy the laws of physics. TL;DR: Whether Omicron or Delta, all SARS-CoV-2 variants are transmitted the same way, so you can reduce risk by using your #SMARTS: ↔️ Space: Keep your distance from other people. 😷 Masks: Keep your nose + mouth covered. 💨 Air: Keep it fresh. 🔄 Read more…
December 1, 2021
What’s new with Omicron?
COVID Variants Vaccines
Jennifer Beam Dowd, PhD
A: IT’S. STILL. TOO. SOON. TO. TELL. We know, the media panic level has been HIGH this week. But the truth is NO expert or TV pundit can predict what will happen with the new variant Omicron right now. We simply don’t have enough data yet on the key questions about the variant: 1) Is Read more…
November 27, 2021
Omicron – Blip or Blow-up?
COVID Variants Uncertainty and Misinformation
Lindsey Leininger, PhD MA
******UPDATE, 1:05 pm EST, 11/27/21: New cases are being reported in other countries. We can expect more of the same as surveillance goes into overdrive. I keep reminding myself that science doesn’t move at the speed of the news cycle. So we won’t know for a while which details are signal and which are noise. Read more…
October 6, 2021
What’s the best MASK to protect me from the Delta variant?
COVID Variants Masks
Jennifer Beam Dowd, PhD
A: A well-fitted, high filtration mask such as N95, KN95, FFP2 or KF94. ⚠️ Delta is more transmissible, in part due to infected people shedding more virus from their nose and mouth. While vaccination is still your #1 defense against Delta, it’s also a good idea to UPGRADE YOUR MASK when you are in higher Read more…
October 5, 2021
When can we expect a variant specific (i.e. Delta variant) booster shot?
COVID Variants Vaccines
Amanda Simanek, PhD MPH
A: Variant specific boosters are currently being tested, but it’s not clear whether we need them just yet. Here is a run-down of ongoing trials: Pfizer/BioNTech has two Phase 2/3 trials ongoing, one with a booster designed to target the Beta variant (the one that emerged in South Africa in late 2020) and one that Read more…
September 2, 2021
California Classroom Outbreak Explained
COVID Variants Infection and Spread School
Jennifer Beam Dowd, PhD
A recent CDC outbreak investigation found that an unvaccinated teacher infected twelve elementary school students out of a class of 24 students in California. All students were too young to be eligible for the vaccine. Key take-aways: ➡️ GET VACCINATED ➡️ KEEP YOUR MASK ON WHILE TALKING!! ➡️ STAY HOME WHEN SICK ➡️ GET VACCINATED Read more…
August 31, 2021
What’s going on with the Delta variant in the UK 🇬🇧? I heard cases were falling?
COVID Variants Data and Metrics
Jennifer Beam Dowd, PhD
A: It’s a mixed bag—cases *have* fallen from their peak but have now plateaued at a high level. TL;DR: ➡️ Cases remain stuck at a high level in the UK, despite high vaccination rates (higher than the US). This speaks to the transmissibility of Delta and means things could get worse in the US. ➡️ Read more…
August 26, 2021
How and why do viruses mutate?
Biology/Immunity COVID Variants Vaccines
Vijaya Knight, MD PhD (D)ABMLI
Q: What does this mean for future SARS-CoV-2 variants? A: After infection, the virus makes lots of copies of itself in the body which can lead to random changes (like typos) in the virus’ genetic code (mutations). While most mutations give no advantage to the virus, with enough chances for mutations, sometimes the virus hits Read more…
A: Yes! Here are some explanations of many of the buzzwords flying 🦟 around right now….variant of concern, neutralizing antibodies, immune evasion and more! *Variant*: A variant is a version of the SARS-CoV-2 virus that has changes to its genetic sequence (i.e., mutations). These changes make it distinct from the other versions of the virus Read more…
OMICRON AND PFIZER/BIONTECH
COVID Variants VaccinesJennifer Beam Dowd, PhD
The trickle of Omicron data is quickly becoming a fountain ⛲. On the heels of yesterday’s Omicron studies, (see summary here) Pfizer today released data showing strong neutralization of Omicron after 3 doses of its vaccine, but a significant reduction for 2 doses. Highlights: ➡️ 2 doses showed significantly reduced neutralization titers against Omicron. ➡️ A Read more…
December 7, 2021
THIS JUST IN: Preliminary Omicron neutralizing antibody study
COVID Variants Vaccines
Jennifer Beam Dowd, PhD
⬇️ TL;DR: IN A LAB DISH (so NOT in real life), antibodies from vaccinated individuals (two doses of Pfizer-BioNTech), were significantly less effective at neutralizing Omicron compared to the original variant—about a 20-40-fold reduction in neutralization. While this is substantially more loss of neutralization than previous variants…this does NOT tell us how well the vaccines Read more…
December 7, 2021
Do COVID-19 vaccines promote the emergence of new variants?
COVID Variants Uncertainty and Misinformation Vaccines
Jennifer Beam Dowd, PhD
A: No. Vaccines REDUCE opportunities for viral replication needed for variants to emerge. Since the recent Omicron news, we are hearing this myth make the rounds again. ➡️ TL;DR: The virus has more opportunity to replicate in unvaccinated populations, creating a FAR bigger risk for the development of SARS-CoV-2 mutations. Even so, the good news Read more…
December 2, 2021
Are normal precautions (masks, distance, ventilation) less effective against new variants?
COVID Variants Staying Safe
Jennifer Beam Dowd, PhD
A: NOPE. Virus mutations STILL don’t defy the laws of physics. TL;DR: Whether Omicron or Delta, all SARS-CoV-2 variants are transmitted the same way, so you can reduce risk by using your #SMARTS: ↔️ Space: Keep your distance from other people. 😷 Masks: Keep your nose + mouth covered. 💨 Air: Keep it fresh. 🔄 Read more…
December 1, 2021
What’s new with Omicron?
COVID Variants Vaccines
Jennifer Beam Dowd, PhD
A: IT’S. STILL. TOO. SOON. TO. TELL. We know, the media panic level has been HIGH this week. But the truth is NO expert or TV pundit can predict what will happen with the new variant Omicron right now. We simply don’t have enough data yet on the key questions about the variant: 1) Is Read more…
November 27, 2021
Omicron – Blip or Blow-up?
COVID Variants Uncertainty and Misinformation
Lindsey Leininger, PhD MA
******UPDATE, 1:05 pm EST, 11/27/21: New cases are being reported in other countries. We can expect more of the same as surveillance goes into overdrive. I keep reminding myself that science doesn’t move at the speed of the news cycle. So we won’t know for a while which details are signal and which are noise. Read more…
October 6, 2021
What’s the best MASK to protect me from the Delta variant?
COVID Variants Masks
Jennifer Beam Dowd, PhD
A: A well-fitted, high filtration mask such as N95, KN95, FFP2 or KF94. ⚠️ Delta is more transmissible, in part due to infected people shedding more virus from their nose and mouth. While vaccination is still your #1 defense against Delta, it’s also a good idea to UPGRADE YOUR MASK when you are in higher Read more…
October 5, 2021
When can we expect a variant specific (i.e. Delta variant) booster shot?
COVID Variants Vaccines
Amanda Simanek, PhD MPH
A: Variant specific boosters are currently being tested, but it’s not clear whether we need them just yet. Here is a run-down of ongoing trials: Pfizer/BioNTech has two Phase 2/3 trials ongoing, one with a booster designed to target the Beta variant (the one that emerged in South Africa in late 2020) and one that Read more…
September 2, 2021
California Classroom Outbreak Explained
COVID Variants Infection and Spread School
Jennifer Beam Dowd, PhD
A recent CDC outbreak investigation found that an unvaccinated teacher infected twelve elementary school students out of a class of 24 students in California. All students were too young to be eligible for the vaccine. Key take-aways: ➡️ GET VACCINATED ➡️ KEEP YOUR MASK ON WHILE TALKING!! ➡️ STAY HOME WHEN SICK ➡️ GET VACCINATED Read more…
August 31, 2021
What’s going on with the Delta variant in the UK 🇬🇧? I heard cases were falling?
COVID Variants Data and Metrics
Jennifer Beam Dowd, PhD
A: It’s a mixed bag—cases *have* fallen from their peak but have now plateaued at a high level. TL;DR: ➡️ Cases remain stuck at a high level in the UK, despite high vaccination rates (higher than the US). This speaks to the transmissibility of Delta and means things could get worse in the US. ➡️ Read more…
August 26, 2021
How and why do viruses mutate?
Biology/Immunity COVID Variants Vaccines
Vijaya Knight, MD PhD (D)ABMLI
Q: What does this mean for future SARS-CoV-2 variants? A: After infection, the virus makes lots of copies of itself in the body which can lead to random changes (like typos) in the virus’ genetic code (mutations). While most mutations give no advantage to the virus, with enough chances for mutations, sometimes the virus hits Read more…
The trickle of Omicron data is quickly becoming a fountain ⛲. On the heels of yesterday’s Omicron studies, (see summary here) Pfizer today released data showing strong neutralization of Omicron after 3 doses of its vaccine, but a significant reduction for 2 doses. Highlights: ➡️ 2 doses showed significantly reduced neutralization titers against Omicron. ➡️ A Read more…
THIS JUST IN: Preliminary Omicron neutralizing antibody study
COVID Variants VaccinesJennifer Beam Dowd, PhD
⬇️ TL;DR: IN A LAB DISH (so NOT in real life), antibodies from vaccinated individuals (two doses of Pfizer-BioNTech), were significantly less effective at neutralizing Omicron compared to the original variant—about a 20-40-fold reduction in neutralization. While this is substantially more loss of neutralization than previous variants…this does NOT tell us how well the vaccines Read more…
December 7, 2021
Do COVID-19 vaccines promote the emergence of new variants?
COVID Variants Uncertainty and Misinformation Vaccines
Jennifer Beam Dowd, PhD
A: No. Vaccines REDUCE opportunities for viral replication needed for variants to emerge. Since the recent Omicron news, we are hearing this myth make the rounds again. ➡️ TL;DR: The virus has more opportunity to replicate in unvaccinated populations, creating a FAR bigger risk for the development of SARS-CoV-2 mutations. Even so, the good news Read more…
December 2, 2021
Are normal precautions (masks, distance, ventilation) less effective against new variants?
COVID Variants Staying Safe
Jennifer Beam Dowd, PhD
A: NOPE. Virus mutations STILL don’t defy the laws of physics. TL;DR: Whether Omicron or Delta, all SARS-CoV-2 variants are transmitted the same way, so you can reduce risk by using your #SMARTS: ↔️ Space: Keep your distance from other people. 😷 Masks: Keep your nose + mouth covered. 💨 Air: Keep it fresh. 🔄 Read more…
December 1, 2021
What’s new with Omicron?
COVID Variants Vaccines
Jennifer Beam Dowd, PhD
A: IT’S. STILL. TOO. SOON. TO. TELL. We know, the media panic level has been HIGH this week. But the truth is NO expert or TV pundit can predict what will happen with the new variant Omicron right now. We simply don’t have enough data yet on the key questions about the variant: 1) Is Read more…
November 27, 2021
Omicron – Blip or Blow-up?
COVID Variants Uncertainty and Misinformation
Lindsey Leininger, PhD MA
******UPDATE, 1:05 pm EST, 11/27/21: New cases are being reported in other countries. We can expect more of the same as surveillance goes into overdrive. I keep reminding myself that science doesn’t move at the speed of the news cycle. So we won’t know for a while which details are signal and which are noise. Read more…
October 6, 2021
What’s the best MASK to protect me from the Delta variant?
COVID Variants Masks
Jennifer Beam Dowd, PhD
A: A well-fitted, high filtration mask such as N95, KN95, FFP2 or KF94. ⚠️ Delta is more transmissible, in part due to infected people shedding more virus from their nose and mouth. While vaccination is still your #1 defense against Delta, it’s also a good idea to UPGRADE YOUR MASK when you are in higher Read more…
October 5, 2021
When can we expect a variant specific (i.e. Delta variant) booster shot?
COVID Variants Vaccines
Amanda Simanek, PhD MPH
A: Variant specific boosters are currently being tested, but it’s not clear whether we need them just yet. Here is a run-down of ongoing trials: Pfizer/BioNTech has two Phase 2/3 trials ongoing, one with a booster designed to target the Beta variant (the one that emerged in South Africa in late 2020) and one that Read more…
September 2, 2021
California Classroom Outbreak Explained
COVID Variants Infection and Spread School
Jennifer Beam Dowd, PhD
A recent CDC outbreak investigation found that an unvaccinated teacher infected twelve elementary school students out of a class of 24 students in California. All students were too young to be eligible for the vaccine. Key take-aways: ➡️ GET VACCINATED ➡️ KEEP YOUR MASK ON WHILE TALKING!! ➡️ STAY HOME WHEN SICK ➡️ GET VACCINATED Read more…
August 31, 2021
What’s going on with the Delta variant in the UK 🇬🇧? I heard cases were falling?
COVID Variants Data and Metrics
Jennifer Beam Dowd, PhD
A: It’s a mixed bag—cases *have* fallen from their peak but have now plateaued at a high level. TL;DR: ➡️ Cases remain stuck at a high level in the UK, despite high vaccination rates (higher than the US). This speaks to the transmissibility of Delta and means things could get worse in the US. ➡️ Read more…
August 26, 2021
How and why do viruses mutate?
Biology/Immunity COVID Variants Vaccines
Vijaya Knight, MD PhD (D)ABMLI
Q: What does this mean for future SARS-CoV-2 variants? A: After infection, the virus makes lots of copies of itself in the body which can lead to random changes (like typos) in the virus’ genetic code (mutations). While most mutations give no advantage to the virus, with enough chances for mutations, sometimes the virus hits Read more…
⬇️ TL;DR: IN A LAB DISH (so NOT in real life), antibodies from vaccinated individuals (two doses of Pfizer-BioNTech), were significantly less effective at neutralizing Omicron compared to the original variant—about a 20-40-fold reduction in neutralization. While this is substantially more loss of neutralization than previous variants…this does NOT tell us how well the vaccines Read more…
Do COVID-19 vaccines promote the emergence of new variants?
COVID Variants Uncertainty and Misinformation VaccinesJennifer Beam Dowd, PhD
A: No. Vaccines REDUCE opportunities for viral replication needed for variants to emerge. Since the recent Omicron news, we are hearing this myth make the rounds again. ➡️ TL;DR: The virus has more opportunity to replicate in unvaccinated populations, creating a FAR bigger risk for the development of SARS-CoV-2 mutations. Even so, the good news Read more…
December 2, 2021
Are normal precautions (masks, distance, ventilation) less effective against new variants?
COVID Variants Staying Safe
Jennifer Beam Dowd, PhD
A: NOPE. Virus mutations STILL don’t defy the laws of physics. TL;DR: Whether Omicron or Delta, all SARS-CoV-2 variants are transmitted the same way, so you can reduce risk by using your #SMARTS: ↔️ Space: Keep your distance from other people. 😷 Masks: Keep your nose + mouth covered. 💨 Air: Keep it fresh. 🔄 Read more…
December 1, 2021
What’s new with Omicron?
COVID Variants Vaccines
Jennifer Beam Dowd, PhD
A: IT’S. STILL. TOO. SOON. TO. TELL. We know, the media panic level has been HIGH this week. But the truth is NO expert or TV pundit can predict what will happen with the new variant Omicron right now. We simply don’t have enough data yet on the key questions about the variant: 1) Is Read more…
November 27, 2021
Omicron – Blip or Blow-up?
COVID Variants Uncertainty and Misinformation
Lindsey Leininger, PhD MA
******UPDATE, 1:05 pm EST, 11/27/21: New cases are being reported in other countries. We can expect more of the same as surveillance goes into overdrive. I keep reminding myself that science doesn’t move at the speed of the news cycle. So we won’t know for a while which details are signal and which are noise. Read more…
October 6, 2021
What’s the best MASK to protect me from the Delta variant?
COVID Variants Masks
Jennifer Beam Dowd, PhD
A: A well-fitted, high filtration mask such as N95, KN95, FFP2 or KF94. ⚠️ Delta is more transmissible, in part due to infected people shedding more virus from their nose and mouth. While vaccination is still your #1 defense against Delta, it’s also a good idea to UPGRADE YOUR MASK when you are in higher Read more…
October 5, 2021
When can we expect a variant specific (i.e. Delta variant) booster shot?
COVID Variants Vaccines
Amanda Simanek, PhD MPH
A: Variant specific boosters are currently being tested, but it’s not clear whether we need them just yet. Here is a run-down of ongoing trials: Pfizer/BioNTech has two Phase 2/3 trials ongoing, one with a booster designed to target the Beta variant (the one that emerged in South Africa in late 2020) and one that Read more…
September 2, 2021
California Classroom Outbreak Explained
COVID Variants Infection and Spread School
Jennifer Beam Dowd, PhD
A recent CDC outbreak investigation found that an unvaccinated teacher infected twelve elementary school students out of a class of 24 students in California. All students were too young to be eligible for the vaccine. Key take-aways: ➡️ GET VACCINATED ➡️ KEEP YOUR MASK ON WHILE TALKING!! ➡️ STAY HOME WHEN SICK ➡️ GET VACCINATED Read more…
August 31, 2021
What’s going on with the Delta variant in the UK 🇬🇧? I heard cases were falling?
COVID Variants Data and Metrics
Jennifer Beam Dowd, PhD
A: It’s a mixed bag—cases *have* fallen from their peak but have now plateaued at a high level. TL;DR: ➡️ Cases remain stuck at a high level in the UK, despite high vaccination rates (higher than the US). This speaks to the transmissibility of Delta and means things could get worse in the US. ➡️ Read more…
August 26, 2021
How and why do viruses mutate?
Biology/Immunity COVID Variants Vaccines
Vijaya Knight, MD PhD (D)ABMLI
Q: What does this mean for future SARS-CoV-2 variants? A: After infection, the virus makes lots of copies of itself in the body which can lead to random changes (like typos) in the virus’ genetic code (mutations). While most mutations give no advantage to the virus, with enough chances for mutations, sometimes the virus hits Read more…
A: No. Vaccines REDUCE opportunities for viral replication needed for variants to emerge. Since the recent Omicron news, we are hearing this myth make the rounds again. ➡️ TL;DR: The virus has more opportunity to replicate in unvaccinated populations, creating a FAR bigger risk for the development of SARS-CoV-2 mutations. Even so, the good news Read more…
Are normal precautions (masks, distance, ventilation) less effective against new variants?
COVID Variants Staying SafeJennifer Beam Dowd, PhD
A: NOPE. Virus mutations STILL don’t defy the laws of physics. TL;DR: Whether Omicron or Delta, all SARS-CoV-2 variants are transmitted the same way, so you can reduce risk by using your #SMARTS: ↔️ Space: Keep your distance from other people. 😷 Masks: Keep your nose + mouth covered. 💨 Air: Keep it fresh. 🔄 Read more…
December 1, 2021
What’s new with Omicron?
COVID Variants Vaccines
Jennifer Beam Dowd, PhD
A: IT’S. STILL. TOO. SOON. TO. TELL. We know, the media panic level has been HIGH this week. But the truth is NO expert or TV pundit can predict what will happen with the new variant Omicron right now. We simply don’t have enough data yet on the key questions about the variant: 1) Is Read more…
November 27, 2021
Omicron – Blip or Blow-up?
COVID Variants Uncertainty and Misinformation
Lindsey Leininger, PhD MA
******UPDATE, 1:05 pm EST, 11/27/21: New cases are being reported in other countries. We can expect more of the same as surveillance goes into overdrive. I keep reminding myself that science doesn’t move at the speed of the news cycle. So we won’t know for a while which details are signal and which are noise. Read more…
October 6, 2021
What’s the best MASK to protect me from the Delta variant?
COVID Variants Masks
Jennifer Beam Dowd, PhD
A: A well-fitted, high filtration mask such as N95, KN95, FFP2 or KF94. ⚠️ Delta is more transmissible, in part due to infected people shedding more virus from their nose and mouth. While vaccination is still your #1 defense against Delta, it’s also a good idea to UPGRADE YOUR MASK when you are in higher Read more…
October 5, 2021
When can we expect a variant specific (i.e. Delta variant) booster shot?
COVID Variants Vaccines
Amanda Simanek, PhD MPH
A: Variant specific boosters are currently being tested, but it’s not clear whether we need them just yet. Here is a run-down of ongoing trials: Pfizer/BioNTech has two Phase 2/3 trials ongoing, one with a booster designed to target the Beta variant (the one that emerged in South Africa in late 2020) and one that Read more…
September 2, 2021
California Classroom Outbreak Explained
COVID Variants Infection and Spread School
Jennifer Beam Dowd, PhD
A recent CDC outbreak investigation found that an unvaccinated teacher infected twelve elementary school students out of a class of 24 students in California. All students were too young to be eligible for the vaccine. Key take-aways: ➡️ GET VACCINATED ➡️ KEEP YOUR MASK ON WHILE TALKING!! ➡️ STAY HOME WHEN SICK ➡️ GET VACCINATED Read more…
August 31, 2021
What’s going on with the Delta variant in the UK 🇬🇧? I heard cases were falling?
COVID Variants Data and Metrics
Jennifer Beam Dowd, PhD
A: It’s a mixed bag—cases *have* fallen from their peak but have now plateaued at a high level. TL;DR: ➡️ Cases remain stuck at a high level in the UK, despite high vaccination rates (higher than the US). This speaks to the transmissibility of Delta and means things could get worse in the US. ➡️ Read more…
August 26, 2021
How and why do viruses mutate?
Biology/Immunity COVID Variants Vaccines
Vijaya Knight, MD PhD (D)ABMLI
Q: What does this mean for future SARS-CoV-2 variants? A: After infection, the virus makes lots of copies of itself in the body which can lead to random changes (like typos) in the virus’ genetic code (mutations). While most mutations give no advantage to the virus, with enough chances for mutations, sometimes the virus hits Read more…
A: NOPE. Virus mutations STILL don’t defy the laws of physics. TL;DR: Whether Omicron or Delta, all SARS-CoV-2 variants are transmitted the same way, so you can reduce risk by using your #SMARTS: ↔️ Space: Keep your distance from other people. 😷 Masks: Keep your nose + mouth covered. 💨 Air: Keep it fresh. 🔄 Read more…
What’s new with Omicron?
COVID Variants VaccinesJennifer Beam Dowd, PhD
A: IT’S. STILL. TOO. SOON. TO. TELL. We know, the media panic level has been HIGH this week. But the truth is NO expert or TV pundit can predict what will happen with the new variant Omicron right now. We simply don’t have enough data yet on the key questions about the variant: 1) Is Read more…
November 27, 2021
Omicron – Blip or Blow-up?
COVID Variants Uncertainty and Misinformation
Lindsey Leininger, PhD MA
******UPDATE, 1:05 pm EST, 11/27/21: New cases are being reported in other countries. We can expect more of the same as surveillance goes into overdrive. I keep reminding myself that science doesn’t move at the speed of the news cycle. So we won’t know for a while which details are signal and which are noise. Read more…
October 6, 2021
What’s the best MASK to protect me from the Delta variant?
COVID Variants Masks
Jennifer Beam Dowd, PhD
A: A well-fitted, high filtration mask such as N95, KN95, FFP2 or KF94. ⚠️ Delta is more transmissible, in part due to infected people shedding more virus from their nose and mouth. While vaccination is still your #1 defense against Delta, it’s also a good idea to UPGRADE YOUR MASK when you are in higher Read more…
October 5, 2021
When can we expect a variant specific (i.e. Delta variant) booster shot?
COVID Variants Vaccines
Amanda Simanek, PhD MPH
A: Variant specific boosters are currently being tested, but it’s not clear whether we need them just yet. Here is a run-down of ongoing trials: Pfizer/BioNTech has two Phase 2/3 trials ongoing, one with a booster designed to target the Beta variant (the one that emerged in South Africa in late 2020) and one that Read more…
September 2, 2021
California Classroom Outbreak Explained
COVID Variants Infection and Spread School
Jennifer Beam Dowd, PhD
A recent CDC outbreak investigation found that an unvaccinated teacher infected twelve elementary school students out of a class of 24 students in California. All students were too young to be eligible for the vaccine. Key take-aways: ➡️ GET VACCINATED ➡️ KEEP YOUR MASK ON WHILE TALKING!! ➡️ STAY HOME WHEN SICK ➡️ GET VACCINATED Read more…
August 31, 2021
What’s going on with the Delta variant in the UK 🇬🇧? I heard cases were falling?
COVID Variants Data and Metrics
Jennifer Beam Dowd, PhD
A: It’s a mixed bag—cases *have* fallen from their peak but have now plateaued at a high level. TL;DR: ➡️ Cases remain stuck at a high level in the UK, despite high vaccination rates (higher than the US). This speaks to the transmissibility of Delta and means things could get worse in the US. ➡️ Read more…
August 26, 2021
How and why do viruses mutate?
Biology/Immunity COVID Variants Vaccines
Vijaya Knight, MD PhD (D)ABMLI
Q: What does this mean for future SARS-CoV-2 variants? A: After infection, the virus makes lots of copies of itself in the body which can lead to random changes (like typos) in the virus’ genetic code (mutations). While most mutations give no advantage to the virus, with enough chances for mutations, sometimes the virus hits Read more…
A: IT’S. STILL. TOO. SOON. TO. TELL. We know, the media panic level has been HIGH this week. But the truth is NO expert or TV pundit can predict what will happen with the new variant Omicron right now. We simply don’t have enough data yet on the key questions about the variant: 1) Is Read more…
Omicron – Blip or Blow-up?
COVID Variants Uncertainty and MisinformationLindsey Leininger, PhD MA
******UPDATE, 1:05 pm EST, 11/27/21: New cases are being reported in other countries. We can expect more of the same as surveillance goes into overdrive. I keep reminding myself that science doesn’t move at the speed of the news cycle. So we won’t know for a while which details are signal and which are noise. Read more…
October 6, 2021
What’s the best MASK to protect me from the Delta variant?
COVID Variants Masks
Jennifer Beam Dowd, PhD
A: A well-fitted, high filtration mask such as N95, KN95, FFP2 or KF94. ⚠️ Delta is more transmissible, in part due to infected people shedding more virus from their nose and mouth. While vaccination is still your #1 defense against Delta, it’s also a good idea to UPGRADE YOUR MASK when you are in higher Read more…
October 5, 2021
When can we expect a variant specific (i.e. Delta variant) booster shot?
COVID Variants Vaccines
Amanda Simanek, PhD MPH
A: Variant specific boosters are currently being tested, but it’s not clear whether we need them just yet. Here is a run-down of ongoing trials: Pfizer/BioNTech has two Phase 2/3 trials ongoing, one with a booster designed to target the Beta variant (the one that emerged in South Africa in late 2020) and one that Read more…
September 2, 2021
California Classroom Outbreak Explained
COVID Variants Infection and Spread School
Jennifer Beam Dowd, PhD
A recent CDC outbreak investigation found that an unvaccinated teacher infected twelve elementary school students out of a class of 24 students in California. All students were too young to be eligible for the vaccine. Key take-aways: ➡️ GET VACCINATED ➡️ KEEP YOUR MASK ON WHILE TALKING!! ➡️ STAY HOME WHEN SICK ➡️ GET VACCINATED Read more…
August 31, 2021
What’s going on with the Delta variant in the UK 🇬🇧? I heard cases were falling?
COVID Variants Data and Metrics
Jennifer Beam Dowd, PhD
A: It’s a mixed bag—cases *have* fallen from their peak but have now plateaued at a high level. TL;DR: ➡️ Cases remain stuck at a high level in the UK, despite high vaccination rates (higher than the US). This speaks to the transmissibility of Delta and means things could get worse in the US. ➡️ Read more…
August 26, 2021
How and why do viruses mutate?
Biology/Immunity COVID Variants Vaccines
Vijaya Knight, MD PhD (D)ABMLI
Q: What does this mean for future SARS-CoV-2 variants? A: After infection, the virus makes lots of copies of itself in the body which can lead to random changes (like typos) in the virus’ genetic code (mutations). While most mutations give no advantage to the virus, with enough chances for mutations, sometimes the virus hits Read more…
******UPDATE, 1:05 pm EST, 11/27/21: New cases are being reported in other countries. We can expect more of the same as surveillance goes into overdrive. I keep reminding myself that science doesn’t move at the speed of the news cycle. So we won’t know for a while which details are signal and which are noise. Read more…
What’s the best MASK to protect me from the Delta variant?
COVID Variants MasksJennifer Beam Dowd, PhD
A: A well-fitted, high filtration mask such as N95, KN95, FFP2 or KF94. ⚠️ Delta is more transmissible, in part due to infected people shedding more virus from their nose and mouth. While vaccination is still your #1 defense against Delta, it’s also a good idea to UPGRADE YOUR MASK when you are in higher Read more…
October 5, 2021
When can we expect a variant specific (i.e. Delta variant) booster shot?
COVID Variants Vaccines
Amanda Simanek, PhD MPH
A: Variant specific boosters are currently being tested, but it’s not clear whether we need them just yet. Here is a run-down of ongoing trials: Pfizer/BioNTech has two Phase 2/3 trials ongoing, one with a booster designed to target the Beta variant (the one that emerged in South Africa in late 2020) and one that Read more…
September 2, 2021
California Classroom Outbreak Explained
COVID Variants Infection and Spread School
Jennifer Beam Dowd, PhD
A recent CDC outbreak investigation found that an unvaccinated teacher infected twelve elementary school students out of a class of 24 students in California. All students were too young to be eligible for the vaccine. Key take-aways: ➡️ GET VACCINATED ➡️ KEEP YOUR MASK ON WHILE TALKING!! ➡️ STAY HOME WHEN SICK ➡️ GET VACCINATED Read more…
August 31, 2021
What’s going on with the Delta variant in the UK 🇬🇧? I heard cases were falling?
COVID Variants Data and Metrics
Jennifer Beam Dowd, PhD
A: It’s a mixed bag—cases *have* fallen from their peak but have now plateaued at a high level. TL;DR: ➡️ Cases remain stuck at a high level in the UK, despite high vaccination rates (higher than the US). This speaks to the transmissibility of Delta and means things could get worse in the US. ➡️ Read more…
August 26, 2021
How and why do viruses mutate?
Biology/Immunity COVID Variants Vaccines
Vijaya Knight, MD PhD (D)ABMLI
Q: What does this mean for future SARS-CoV-2 variants? A: After infection, the virus makes lots of copies of itself in the body which can lead to random changes (like typos) in the virus’ genetic code (mutations). While most mutations give no advantage to the virus, with enough chances for mutations, sometimes the virus hits Read more…
A: A well-fitted, high filtration mask such as N95, KN95, FFP2 or KF94. ⚠️ Delta is more transmissible, in part due to infected people shedding more virus from their nose and mouth. While vaccination is still your #1 defense against Delta, it’s also a good idea to UPGRADE YOUR MASK when you are in higher Read more…
When can we expect a variant specific (i.e. Delta variant) booster shot?
COVID Variants VaccinesAmanda Simanek, PhD MPH
A: Variant specific boosters are currently being tested, but it’s not clear whether we need them just yet. Here is a run-down of ongoing trials: Pfizer/BioNTech has two Phase 2/3 trials ongoing, one with a booster designed to target the Beta variant (the one that emerged in South Africa in late 2020) and one that Read more…
September 2, 2021
California Classroom Outbreak Explained
COVID Variants Infection and Spread School
Jennifer Beam Dowd, PhD
A recent CDC outbreak investigation found that an unvaccinated teacher infected twelve elementary school students out of a class of 24 students in California. All students were too young to be eligible for the vaccine. Key take-aways: ➡️ GET VACCINATED ➡️ KEEP YOUR MASK ON WHILE TALKING!! ➡️ STAY HOME WHEN SICK ➡️ GET VACCINATED Read more…
August 31, 2021
What’s going on with the Delta variant in the UK 🇬🇧? I heard cases were falling?
COVID Variants Data and Metrics
Jennifer Beam Dowd, PhD
A: It’s a mixed bag—cases *have* fallen from their peak but have now plateaued at a high level. TL;DR: ➡️ Cases remain stuck at a high level in the UK, despite high vaccination rates (higher than the US). This speaks to the transmissibility of Delta and means things could get worse in the US. ➡️ Read more…
August 26, 2021
How and why do viruses mutate?
Biology/Immunity COVID Variants Vaccines
Vijaya Knight, MD PhD (D)ABMLI
Q: What does this mean for future SARS-CoV-2 variants? A: After infection, the virus makes lots of copies of itself in the body which can lead to random changes (like typos) in the virus’ genetic code (mutations). While most mutations give no advantage to the virus, with enough chances for mutations, sometimes the virus hits Read more…
A: Variant specific boosters are currently being tested, but it’s not clear whether we need them just yet. Here is a run-down of ongoing trials: Pfizer/BioNTech has two Phase 2/3 trials ongoing, one with a booster designed to target the Beta variant (the one that emerged in South Africa in late 2020) and one that Read more…
California Classroom Outbreak Explained
COVID Variants Infection and Spread SchoolJennifer Beam Dowd, PhD
A recent CDC outbreak investigation found that an unvaccinated teacher infected twelve elementary school students out of a class of 24 students in California. All students were too young to be eligible for the vaccine. Key take-aways: ➡️ GET VACCINATED ➡️ KEEP YOUR MASK ON WHILE TALKING!! ➡️ STAY HOME WHEN SICK ➡️ GET VACCINATED Read more…
August 31, 2021
What’s going on with the Delta variant in the UK 🇬🇧? I heard cases were falling?
COVID Variants Data and Metrics
Jennifer Beam Dowd, PhD
A: It’s a mixed bag—cases *have* fallen from their peak but have now plateaued at a high level. TL;DR: ➡️ Cases remain stuck at a high level in the UK, despite high vaccination rates (higher than the US). This speaks to the transmissibility of Delta and means things could get worse in the US. ➡️ Read more…
August 26, 2021
How and why do viruses mutate?
Biology/Immunity COVID Variants Vaccines
Vijaya Knight, MD PhD (D)ABMLI
Q: What does this mean for future SARS-CoV-2 variants? A: After infection, the virus makes lots of copies of itself in the body which can lead to random changes (like typos) in the virus’ genetic code (mutations). While most mutations give no advantage to the virus, with enough chances for mutations, sometimes the virus hits Read more…
A recent CDC outbreak investigation found that an unvaccinated teacher infected twelve elementary school students out of a class of 24 students in California. All students were too young to be eligible for the vaccine. Key take-aways: ➡️ GET VACCINATED ➡️ KEEP YOUR MASK ON WHILE TALKING!! ➡️ STAY HOME WHEN SICK ➡️ GET VACCINATED Read more…
What’s going on with the Delta variant in the UK 🇬🇧? I heard cases were falling?
COVID Variants Data and MetricsJennifer Beam Dowd, PhD
A: It’s a mixed bag—cases *have* fallen from their peak but have now plateaued at a high level. TL;DR: ➡️ Cases remain stuck at a high level in the UK, despite high vaccination rates (higher than the US). This speaks to the transmissibility of Delta and means things could get worse in the US. ➡️ Read more…
August 26, 2021
How and why do viruses mutate?
Biology/Immunity COVID Variants Vaccines
Vijaya Knight, MD PhD (D)ABMLI
Q: What does this mean for future SARS-CoV-2 variants? A: After infection, the virus makes lots of copies of itself in the body which can lead to random changes (like typos) in the virus’ genetic code (mutations). While most mutations give no advantage to the virus, with enough chances for mutations, sometimes the virus hits Read more…
A: It’s a mixed bag—cases *have* fallen from their peak but have now plateaued at a high level. TL;DR: ➡️ Cases remain stuck at a high level in the UK, despite high vaccination rates (higher than the US). This speaks to the transmissibility of Delta and means things could get worse in the US. ➡️ Read more…
How and why do viruses mutate?
Biology/Immunity COVID Variants VaccinesVijaya Knight, MD PhD (D)ABMLI
Q: What does this mean for future SARS-CoV-2 variants? A: After infection, the virus makes lots of copies of itself in the body which can lead to random changes (like typos) in the virus’ genetic code (mutations). While most mutations give no advantage to the virus, with enough chances for mutations, sometimes the virus hits Read more…
Q: What does this mean for future SARS-CoV-2 variants? A: After infection, the virus makes lots of copies of itself in the body which can lead to random changes (like typos) in the virus’ genetic code (mutations). While most mutations give no advantage to the virus, with enough chances for mutations, sometimes the virus hits Read more…