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Why do children have less severe COVID-19 than adults?

Biology/Immunity Families/Kids Vaccines

A: A better innate immune response may explain milder COVID-19 disease in kids, but they still CAN and DO get infected and transmit SARS-CoV-2, especially the more transmissible Delta variant. 👉🏽 TL;DR. Children have fewer ACE2 receptors, a more robust innate immune system, and produce more anti-viral proteins (like type 1 interferons) than adults. These Read more…

Is immunity from natural COVID infection “better” than vaccine immunity?

Biology/Immunity Vaccines

A: No. Getting vaccinated is by far the safest way to develop immunity to SARS-CoV-2. If you’ve already been infected, getting vaccinated still provides you with the best protection-in fact likely *better* than either previous infection or the vaccine alone. A recent study from Israel created waves with findings that people with previous COVID-19 infection Read more…

Will the COVID-19 vaccines encourage the emergence of new variants or immune evasion?

Biology/Immunity COVID Variants Vaccines

A: No. Vaccines REDUCE opportunities for viral replication needed for variants to emerge. ➡️ TL;DR: The virus has more opportunity to replicate in unvaccinated populations, creating a FAR bigger risk for the development of SARS-CoV-2 mutations. Even so, the good news is that the emergence of variants that fully evade vaccine induced immunity is considered Read more…

How does natural immunity to SARS-CoV-2 infection differ from immunity generated by COVID-19 vaccines?

Biology/Immunity Vaccines

A. COVID-19 vaccines induce higher levels and a broader range of neutralizing antibodies to the receptor binding domain (RBD) of the spike protein than does natural infection. Vaccine-induced antibodies are less likely to be affected by changes in the RBD seen in the current SARS-CoV-2 variants, and are therefore more likely to be more effective Read more…

Can COVID-19 vaccines alter or weaken my existing immune response against other viruses?

Biology/Immunity Vaccines

A. No. COVID-19 vaccines do not affect existing immune cells or antibodies that you have made against other viruses. Nor will it prevent you from making an immune response to another virus when you encounter it. 👉 TL;DR: Our immune system is designed for IMMENSE flexibility to be able to respond to thousands of pathogens Read more…

What is gene therapy? How is it different from vaccines?

Biology/Immunity Uncertainty and Misinformation Vaccines

A: Gene therapies treat diseases using genetic tools. They usually work by making lasting changes to your DNA — the genetic “cookbook” that provides instructions to make you. Vaccines, by contrast, deliver a short-lived signal (e.g. a burst of protein), then disappear. Vaccines and gene therapies both use customized genetic tools to achieve their goals. Read more…

Can COVID-19 cause erectile dysfunction (ED) or affect sperm? (Updated 5/24/21)

Biology/Immunity Clinical Symptoms

A: It’s possible. #VaxUpToGetItUp TL;DR: Due to its impact on inflammation and the vascular system, it is biologically plausible that COVID-19 contributes to erectile dysfunction. But as with much COVID-19 research more, ahem, hard data is needed. COVID-19 infection HAS been associated with a reduction in sperm counts in early research. A recent study found Read more…

Dear Pandemic COVID Q&A

Biology/Immunity Families/Kids Infection and Spread Vaccines Videos

Malia Jones will be live with Dear Pandemic contributor Dr. Chana Davis! Dr. Davis is a geneticist by training and has experience in cancer research, personalized medicine, and nutrition. She’s also the author of Fueled by Science, a blog and podcast. We’ll be talking about mix-and-match vaccines, origins of the COVID-19 virus, and more! ➡️ Read more…

Dear Pandemic COVID Q&A

Biology/Immunity Families/Kids Vaccines Videos

Malia Jones of Dear Pandemic and Alison Bernstein of Mommy, PhD and SciMoms are teaming up to talk blood donations, CDC mask guidance, kids’ vaccines, and herd immunity. ➡️ Welcome, Intros, and chit chat (0:00-1:58) ➡️ Will blood donation after vaccination lessen my immunity or provide immunity to the person receiving my blood? (2:00-3:30) ➡️ Read more…