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Immunology 101 Video

Biology/Immunity Vaccines

Hi Awesome Nerds! As a “booster” to our recent post on vaccine developments, we want to share with you all an amazing 8-minute video on “Immunology 101” made by Prof. Akiko Iwasaki, Professor of Immunobiology at Yale School of Medicine. Watch with your kids, it’s very accessible and the visualizations are great!! Link to original Read more…

What is the real risk of death from COVID-19? Is it actually worse than the flu?

Biology/Immunity Infection and Spread Uncertainty and Misinformation

A: It’s complicated…. but YES! As a demographer and epidemiologist, mortality rates are in my wheelhouse so to speak, but getting a handle on COVID-19 has challenged us all. First some definitions: Case Fatality Rate (CFR): % of confirmed cases who die. In the U.S., the estimated CFR is currently 4.33% In the U.K., the Read more…

Maybe this increase in cases is good…. aren’t we getting closer to herd immunity?

Biology/Immunity Data and Metrics Infection and Spread

A: NO and NO! It’s been a while since we touched on herd immunity, so first some quick review. If we think of SARS-CoV-2 infections as sparks, uninfected people are the fuel. The very basic idea of herd immunity is that individuals who are already immune–either through previous infection or a vaccine–act as a “firewall” Read more…

A lot has changed over the past few months. Can you explain how the coronavirus (also known as SARS-Co-V-2) infects the body and how it can be stopped?

Biology/Immunity Infection and Spread

A: We love this brilliant series of illustrations on how the coronavirus takes hold in the body as well as potential drug and vaccine targets. Here is a quick summary of what you will see. -The virus enters cells through the ACE2 receptor and then replicates and breaks out—>Once it breaks out, it can either Read more…

Why are men more likely to be hospitalized and die from COVID than women?

Biology/Immunity Clinical Symptoms Families/Kids

A: Most likely due to biological sex differences in immune function, though other social and behavioral factors may contribute as well. Sadly, men are more likely be hospitalized, admitted to the ICU, and die from COVID-19 than women. This pattern first emerged in China and has been relatively consistent across countries, supporting the notion of Read more…

I heard you say on the Dear Pandemic NG Live that the new COVID-19 vaccine candidate from Moderna is a new type of vaccine. Can you explain that?

Biology/Immunity Vaccines

A: We recently heard reports from the pharmaceutical company Moderna that they had a successful early trial of a vaccine for SARS-CoV-2. The way this vaccine candidate works is completely different from previous vaccines that you have likely had. It’s called an mRNA vaccine. In order to explain this, we’re going to take a deeper Read more…

Should I just get it over with and go to a ‘COVID party’?

Biology/Immunity Infection and Spread Staying Safe

A: For the love of peanut butter and jelly, please NO, 1000 X NO! “Health officials in a county in southern Washington state say a rise in coronavirus cases is linked to “COVID-19 parties.” NBC News Link “Walla Walla County health officials are receiving reports of COVID-19 parties occurring in our community, where noninfected people Read more…

What actually is herd immunity anyway?

Biology/Immunity Infection and Spread

A: The term “herd immunity,” also sometimes called community immunity, refers to a situation where a lot of people in a population are not susceptible to a virus–either because they have already had it and are unlikely to get it again, or because they’ve been vaccinated. That is to say, their immune systems have been Read more…

Should those who have had COVID-19 and recovered be issued an “immunity passport” or “risk-free certificate”?

Biology/Immunity Infection and Spread

A: The World Health Organization states, “At this point in the pandemic, there is not enough evidence about the effectiveness of antibody-mediated immunity to guarantee the accuracy of an “immunity passport” or “risk-free certificate.”” Main reasons why: Laboratory tests that detect antibodies to SARS-CoV-2 in people need further validation to determine their accuracy and reliability Read more…